Description

Bromo-2-Propynyl-Magnesium is a highly reactive organometallic reagent, specifically a Grignard reagent, used for the introduction of the bromo-2-propynyl (propargyl bromide) moiety. Its value lies in enabling efficient carbon-carbon bond formation, making it a critical building block for synthesizing complex organic molecules. This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise and scalable synthetic pathways.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing active pharmaceutical ingredients (APIs), particularly those containing alkyne or propargyl functional groups.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators.
• Material Science Research: Building block for creating specialized polymers, dendrimers, and organic electronic materials.
• Cross-Coupling Reactions: Serves as a nucleophile in palladium-catalyzed reactions (e.g., Sonogashira, Negishi) to form conjugated systems.
• Fine Chemical Production: Enables the synthesis of specialty chemicals, flavors, and fragrances requiring propargyl architecture.
• Academic & Industrial R&D: A versatile tool for methodological development and exploring new synthetic routes in organic chemistry.

Basic Information

Product Name	Bromo-2-Propynyl-Magnesium
CAS No.	18295-60-8
Molecular Formula	C3H4BrMg
Molecular Weight	135.27 g/mol
Synonyms	Magnesium, bromo(2-propynyl)-; Propargylmagnesium bromide; 2-Propyn-1-ylmagnesium bromide; 3-Bromoprop-1-yn-1-ylmagnesium; Bromo(prop-2-yn-1-yl)magnesium; (Bromomagnesio)propyne; Bromo(2-propynyl)magnesium
EINECS	Contact for details

Quality Control

Our Bromo-2-Propynyl-Magnesium is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for sensitive synthetic applications. Quality is assured through rigorous analytical testing, including titration to determine active reagent concentration and purity. A Certificate of Analysis (COA) detailing concentration, solvent, and impurity profiles is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile, hygroscopic (moisture-sensitive), and easily oxidized nature, this reagent must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Recommended storage temperature is 2-8°C. Keep away from heat, sparks, open flames, and incompatible materials such as strong acids and oxidizing agents.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in specified solvent)	0.5M - 2.0M (Typical)
Assay (Titration)	≥ 95%
Solvent	THF, Diethyl ether, or specified

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.