Description

Hexahydro-2-Oxo-1H-Azepin-1-Ylmagnesium Iodide is a highly reactive organomagnesium reagent, specifically a Grignard reagent, used for the introduction of the 1-azacycloheptan-2-one moiety. This compound matters for its role as a key building block in advanced organic synthesis, enabling the efficient construction of complex nitrogen-containing heterocycles. Pharmaceutical and agrochemical research and development teams need it for creating novel active ingredients, particularly in the synthesis of lactam-based scaffolds and other seven-membered ring systems.

Application

• Pharmaceutical Intermediate: Critical for the synthesis of novel lactam-based drug candidates, including potential antibiotics and neurological agents.
• Agrochemical Synthesis: Used in the research and development of new herbicides and fungicides with complex heterocyclic structures.
• Material Science Research: Employed in the creation of specialty polymers and functional materials containing nitrogen heterocycles.
• Academic & R&D Laboratories: Serves as a specialized reagent for methodological development in organic chemistry and heterocyclic compound synthesis.
• Fine Chemical Production: Applied in the custom synthesis of high-value, complex organic molecules for various industrial applications.

Basic Information

Product Name	Hexahydro-2-Oxo-1H-Azepin-1-Ylmagnesium Iodide
CAS No.	101678-60-8
Molecular Formula	C6H10MgNIO
Molecular Weight	263.36 g/mol
Synonyms	1-(Iodomagnesio)-2-azacycloheptanone; 2-Azacycloheptanone, 1-(iodomagnesio)-; Hexahydro-2-oxo-1H-azepin-1-ylmagnesium iodide; Caprolactam magnesium iodide Grignard reagent; ε-Caprolactam magnesium iodide; 1-Grignard-ε-caprolactam; (Hexahydro-2-oxo-1H-azepin-1-yl)magnesium iodide
EINECS	Contact for details

Quality Control

Every batch of our Hexahydro-2-Oxo-1H-Azepin-1-Ylmagnesium Iodide undergoes rigorous analytical testing to ensure consistency and high reactivity. We provide comprehensive Certificates of Analysis (COA) detailing assay purity, solution concentration, and impurity profiles. Our quality management system adheres to cGMP principles where applicable, supporting its use in regulated research environments.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C. Due to its hygroscopic and moisture-sensitive nature, the container must be kept in a dry environment and handled under anhydrous conditions to prevent decomposition.

Specification

Item	Specification
Appearance	Solution (typically in THF or Ether)
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 0.5 M in solvent
Purity (HPLC)	≥ 95% (of active Grignard species)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.