Description

3-Biphenylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone organometallic compound for advanced organic synthesis. Its value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the construction of complex biphenyl and polyaromatic frameworks. This reagent is essential for research chemists and process development scientists in the pharmaceutical, agrochemical, and materials science industries, where it is used to synthesize active ingredients, ligands, and organic electronic materials.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for creating biphenyl-based active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Development: Used in the production of advanced herbicides, fungicides, and plant growth regulators with biphenyl cores.
• Materials Science Research: Crucial for synthesizing organic ligands for catalysis, monomers for conductive polymers, and components for OLEDs and other electronic materials.
• Cross-Coupling Reactions: Serves as a critical reagent in Kumada, Negishi, and other transition-metal-catalyzed cross-coupling reactions to form biaryl structures.
• Nucleophilic Addition Reactions: Employed for adding the biphenyl moiety to carbonyl compounds (aldehydes, ketones, esters) and other electrophiles.
• Fine Chemical and Specialty Chemical Production: Used in the custom synthesis of complex, high-value organic molecules for various industrial applications.

Basic Information

Product Name	3-Biphenylmagnesium Bromide
CAS No.	103068-18-4
Molecular Formula	C12H9BrMg
Molecular Weight	257.41 g/mol
Synonyms	3-Phenylphenylmagnesium Bromide; m-Biphenylmagnesium Bromide; (1,1'-Biphenyl]-3-ylmagnesium Bromide; 3-Biphenylylmagnesium Bromide; Magnesium, bromo(1,1'-biphenyl-3-yl)-; Grignard Reagent 3-BiphenylMgBr; 3-Biphenyl Grignard Reagent
EINECS	Contact for details

Quality Control

Every batch of our 3-Biphenylmagnesium Bromide is manufactured and handled under stringent inert atmosphere conditions to ensure reactivity and purity. We provide comprehensive Certificates of Analysis (COA) detailing concentration (typically supplied as a solution in THF or diethyl ether), assay, and impurity profiles. Our quality systems are designed to support cGMP and ISO standards for customers in regulated industries, ensuring traceability and consistency for critical synthesis steps.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized (store under inert atmosphere) and highly volatile. For solutions, store under a dry, inert gas (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep away from heat, sparks, open flames, and strong oxidizers. Use only in a well-ventilated area or fume hood.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow or brown
Concentration	Typically 0.5 M to 1.0 M in THF or Diethyl Ether
Assay (Titration)	≥ 95% (as Grignard reagent)
Identification (IR)	Conforms to structure
Free Magnesium	Reported on COA
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.