Description

2,6-Difluorobenzylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in fine chemical synthesis. Its core value lies in enabling the efficient introduction of the 2,6-difluorobenzyl group into complex molecular frameworks, a key step in constructing advanced intermediates. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and agrochemical industries, where it serves as a critical building block for active ingredients and novel compounds.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for the production of active pharmaceutical ingredients (APIs), particularly in the development of fluorinated drug candidates.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and insecticides where the difluorobenzyl moiety enhances biological activity and stability.
• Liquid Crystal & OLED Material Production: Serves as a precursor in the creation of fluorinated aromatic compounds for electronic display and lighting applications.
• Organic Synthesis & Research: A versatile reagent for carbon-carbon bond formation in academic and industrial research laboratories for creating novel fluorinated aromatic structures.
• Fluorinated Polymer Modifiers: Employed in the synthesis of monomers that impart specific properties like chemical resistance or thermal stability to high-performance polymers.

Basic Information

Product Name	2,6-Difluorobenzylmagnesium Bromide
CAS No.	107549-26-8
Molecular Formula	C7H5BrF2Mg
Molecular Weight	231.32 g/mol
Synonyms	Magnesium, bromo(2,6-difluorophenyl)methyl-; (2,6-Difluorobenzyl)magnesium bromide; 2,6-Difluorobenzylmagnesium bromide solution; 1-(Bromomagnesio)methyl-2,6-difluorobenzene; Grignard reagent 2,6-difluorobenzyl; Bromo(2,6-difluorobenzyl)magnesium
EINECS	Contact for details

Quality Control

Our 2,6-Difluorobenzylmagnesium Bromide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent composition, to ensure consistency and reliability for your synthetic processes. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and highly volatile. It must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For prolonged stability, storage at recommended cold chain temperatures (typically 2-8°C) is advised. Keep away from moisture, heat, and incompatible materials such as acids, water, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to light yellow solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Purity (GC/HPLC)	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.