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Magnesium, Bromo(4-Bromophenyl)- CAS NO 18620-02-5
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CAS No.:18620-02-5
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Magnesium, Bromo(4-Bromophenyl)- is a highly reactive organomagnesium compound, specifically a Grignard reagent, essential for forming carbon-carbon bonds in complex organic synthesis. Its value lies in its ability to act as a powerful nucleophile and strong base, enabling the production of pharmaceuticals, agrochemicals, and advanced materials. This reagent is primarily needed by R&D chemists and process development scientists in the pharmaceutical, fine chemical, and material science industries for constructing complex molecular architectures.
Application
- Pharmaceutical Intermediate Synthesis: A key building block for introducing the 4-bromophenyl moiety into target molecules during the development of active pharmaceutical ingredients (APIs).
- Fine Chemical Production: Used in the manufacture of specialty chemicals, including liquid crystals, OLED materials, and organic ligands for catalysis.
- Agrochemical Research: Employed in the synthesis of novel herbicides, fungicides, and plant growth regulators that require specific aryl-bromide structures.
- Cross-Coupling Reactions: Serves as a crucial reagent in Kumada cross-coupling reactions for the formation of biaryl compounds, a common scaffold in many functional materials.
- Polymer Chemistry: Utilized as an initiator or modifying agent in the synthesis of specialized polymers with tailored properties.
- Academic & Industrial R&D: A fundamental tool for methodological development and exploratory synthesis in chemistry laboratories worldwide.
Basic Information
| Product Name | Magnesium, Bromo(4-Bromophenyl)- |
| CAS No. | 18620-02-5 |
| Molecular Formula | C6H4Br2Mg |
| Molecular Weight | 260.21 g/mol |
| Synonyms | (4-Bromophenyl)magnesium bromide; 4-Bromophenylmagnesium bromide; p-Bromophenylmagnesium bromide; 1-Bromo-4-(bromomagnesio)benzene; Grignard reagent, p-Bromophenylmagnesium bromide; Magnesium, bromo(4-bromophenyl)-; (p-Bromophenyl)magnesium bromide |
| EINECS | Contact for details |
Quality Control
Every batch of Magnesium, Bromo(4-Bromophenyl)- is manufactured and handled under strict inert atmosphere conditions to ensure reactivity and purity. Our quality control process includes rigorous titration to determine the precise concentration of the active Grignard reagent in solution. Certificates of Analysis (COA) are provided with each shipment, detailing assay, solvent content, and visual inspection results to guarantee consistency and performance for your critical synthetic steps.
Storage
Preserve in a tightly closed container, protected from light. This product is highly volatile and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. Keep away from moisture, strong acids, and oxidizing agents. Use appropriate ventilation and explosion-proof equipment in handling areas.
Specification
| Item | Specification |
|---|---|
| Appearance | Clear solution, typically gray to brown |
| Concentration (in specified solvent) | 0.5 M to 2.0 M (Custom concentrations available) |
| Assay (by Titration) | ≥ 95% (as Grignard reagent) |
| Solvent | Typically Tetrahydrofuran (THF) or Diethyl Ether |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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Each batch undergoes strict QC, accompanied by COA, MSDS, and full compliance with international standards.
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