Description

4-Methyl-1-Naphthylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, essential for forming carbon-carbon bonds in complex organic syntheses. Its value lies in its ability to introduce the 4-methyl-1-naphthyl moiety, a versatile aromatic building block, into target molecules with high efficiency and selectivity. This compound is a critical intermediate for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors, particularly for developing active pharmaceutical ingredients (APIs), liquid crystals, and specialty polymers.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of novel drug candidates, especially those containing complex naphthalene-based structures for therapeutic applications.
• Agrochemical Synthesis: Used to construct advanced active ingredients for crop protection products, leveraging the stability and reactivity of the naphthyl group.
• Material Science Research: Serves as a precursor for creating organic semiconductors, liquid crystals, and photoconductive materials used in electronic devices.
• Fine Chemical Production: Employed in the multi-step synthesis of dyes, pigments, and other high-value aromatic specialty chemicals.
• Catalyst Ligand Development: Acts as a starting material for synthesizing sophisticated ligand frameworks used in homogeneous catalysis.
• Academic & R&D Laboratories: A fundamental tool for methodological development and exploratory organic chemistry in research institutions.

Basic Information

Product Name	4-Methyl-1-Naphthylmagnesium Bromide
CAS No.	115913-58-1
Molecular Formula	C11H9BrMg
Molecular Weight	245.40 g/mol
Synonyms	1-(4-Methylnaphthyl)magnesium bromide; 4-Methyl-1-naphthalenemagnesium bromide; (4-Methylnaphthalen-1-yl)magnesium bromide; 4-Methyl-1-naphthyl Grignard reagent; Magnesium, bromo(4-methyl-1-naphthalenyl)-; p-Methyl-1-naphthylmagnesium bromide; 1-Bromomagnesio-4-methylnaphthalene
EINECS	Contact for details

Quality Control

Every batch of 4-Methyl-1-Naphthylmagnesium Bromide is produced and handled under stringent quality protocols, typically supplied as a solution in tetrahydrofuran or diethyl ether. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing assay (by titration), concentration, and solution stability are available upon request. We support cGMP and ISO 9001 compliant manufacturing for critical applications.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive nature, this reagent must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. The storage area should be cool, well-ventilated, and away from sources of ignition and moisture.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light brown
Concentration	0.5 M in THF or Et2O (or as specified)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.