Description

3,4-(Ethylenedioxy)Phenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, with the CAS number 107549-16-6. This compound is a critical building block in advanced organic synthesis, enabling the efficient formation of carbon-carbon bonds to construct complex molecular architectures. It is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require high-purity intermediates for the development of active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key reagent for constructing complex heterocycles and bioactive molecules, particularly in the development of central nervous system (CNS) and cardiovascular drugs.
• Agrochemical Active Ingredient Production: Used in the synthesis of novel herbicides, fungicides, and insecticides that require the 3,4-(ethylenedioxy)phenyl moiety.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and transition metal complexes.
• Functional Material Research: Employed in the synthesis of organic semiconductors, OLED materials, and conductive polymers where the ethylenedioxy bridge modifies electronic properties.
• Fine Chemical and Flavor/Fragrance Synthesis: Used to introduce the phenyl ring with an oxygenated functional group pattern into target molecules.
• Academic and R&D Laboratories: A valuable tool for methodological development in organic chemistry and exploratory synthesis for new chemical entities.

Basic Information

Product Name	3,4-(Ethylenedioxy)Phenylmagnesium Bromide
CAS No.	107549-16-6
Molecular Formula	C8H7BrMgO2
Molecular Weight	239.35 g/mol
Synonyms	1,2-Benzodioxol-5-ylmagnesium bromide; 3,4-(Ethylenedioxy)phenylmagnesium bromide; 5-Magnesio-1,3-benzodioxole bromide; 1,3-Benzodioxol-5-ylmagnesium bromide; 3,4-Methylenedioxyphenylmagnesium bromide (common name); 5-Bromo-1,3-benzodioxole magnesium derivative; Grignard reagent from 5-bromo-1,3-benzodioxole
EINECS	Contact for details

Quality Control

Every batch of 3,4-(Ethylenedioxy)Phenylmagnesium Bromide is manufactured and handled under strict inert atmosphere conditions to ensure reactivity and purity. Our quality assurance includes rigorous analytical testing, with titration to determine the precise concentration of the Grignard reagent in solution. We provide comprehensive Certificates of Analysis (COA) that detail assay, solvent content, and absence of major impurities, supporting cGMP and ISO 9001 standards for traceability and reliability in your supply chain.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile, easily oxidized, and reacts violently with moisture and protic solvents. It must be stored under a dry, inert atmosphere (argon or nitrogen) at 2-8°C. The container should be kept in a cool, well-ventilated area, away from heat, sparks, and open flames. Allow the sealed container to reach room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light brown
Concentration (by Titration)	0.5 M in THF or as specified
Assay (Active Grignard)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	≤ 50 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.