Description

3,4-Dimethylphenylmagnesium Chloride is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry. Its core value lies in its ability to act as a powerful nucleophile and carbon nucleophile source for the formation of new carbon-carbon bonds, a fundamental transformation in constructing complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is employed to introduce the versatile 3,4-dimethylphenyl moiety into target molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for creating active pharmaceutical ingredients (APIs), particularly in the development of compounds with specific aromatic substitution patterns.
• Agrochemical Production: Used in the synthesis of herbicides, fungicides, and insecticides where the dimethylphenyl group contributes to biological activity and stability.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis and metal-organic frameworks (MOFs).
• Fine Chemical and Specialty Material Manufacturing: Employed in the production of dyes, pigments, liquid crystals, and organic electronic materials.
• Academic and R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry research.
• Cross-Coupling Reactions: Utilized in Kumada, Negishi, and related cross-coupling methodologies to form biaryl and other complex structures.

Basic Information

Item	Details
Product Name	3,4-Dimethylphenylmagnesium Chloride
CAS No.	102928-12-1
Molecular Formula	C8H9ClMg
Molecular Weight	164.91 g/mol
Synonyms	3,4-Dimethylphenylmagnesium Chloride; (3,4-Dimethylphenyl)magnesium Chloride; 1-Magnesio-3,4-dimethylbenzene Chloride; Grignard Reagent 3,4-DimethylphenylMgCl; 3,4-Xylylmagnesium Chloride; Magnesium, chloro(3,4-dimethylphenyl)-; 3,4-Dimethylbenzylmagnesium Chloride (common name variant)
EINECS	Contact for details

Quality Control

Our 3,4-Dimethylphenylmagnesium Chloride is manufactured and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for critical synthetic applications. Quality is assured through comprehensive analytical testing, including titration for assay determination and impurity profiling. A Certificate of Analysis (COA) detailing purity, concentration, and solvent data is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent degradation. This material is hygroscopic (moisture-sensitive) and easily oxidized; all handling and aliquoting must be performed using standard Schlenk line or glovebox techniques under anhydrous conditions.

Specification

Item	Specification
Appearance	Clear, brown to dark brown solution
Identification (IR)	Conforms
Assay (Titration)	0.5 M to 2.0 M in THF or Diethyl Ether
Concentration	Specified on COA (± 10%)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.