Description

2-Thioanisolemagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, widely used in advanced synthetic chemistry. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon and carbon-sulfur bonds, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for the synthesis of sulfur-containing heterocycles and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate Synthesis: A key building block for constructing sulfur-containing drug candidates and active pharmaceutical ingredients (APIs).
• Agrochemical Development: Used in the research and production of novel herbicides, fungicides, and insecticides that incorporate thioether functionalities.
• Material Science Research: Employed in the synthesis of organic semiconductors, ligands for catalysis, and advanced polymers with specific electronic properties.
• Fine Chemical Manufacturing: Serves as a critical reagent for the custom synthesis of complex, high-value specialty chemicals and flavors/fragrances intermediates.
• Academic & R&D Laboratories: A valuable tool for methodological development in organic synthesis and exploring new reaction pathways in organometallic chemistry.

Basic Information

Item	Detail
Product Name	2-Thioanisolemagnesium Bromide
CAS No.	99346-84-6
Molecular Formula	C7H7BrMgS
Molecular Weight	227.40 g/mol
Synonyms	(2-Methylthiophenyl)magnesium bromide; 2-(Methylthio)phenylmagnesium bromide; o-(Methylthio)phenylmagnesium bromide; 2-Thioanisole magnesium bromide solution; 2-Methylthiophenylmagnesium bromide; Grignard reagent from 2-bromothioanisole; Bromo(2-methylthiophenyl)magnesium
EINECS	Contact for details

Quality Control

Every batch of 2-Thioanisolemagnesium Bromide is manufactured and tested under stringent quality management protocols to ensure consistency and reliability for your critical syntheses. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as concentration (typically supplied as a solution in THF or diethyl ether), assay by titration, and impurity profile. Our quality commitment aligns with cGMP principles where applicable, supporting development from research to commercial scale.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being highly volatile, hygroscopic (moisture-sensitive), and easily oxidized (store under inert atmosphere), this reagent must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures of 2°C to 8°C. Handle and dispense only in a controlled, moisture-free environment using standard Schlenk or glovebox techniques to maintain purity and reactivity.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration	0.5 M to 2.0 M in specified solvent (e.g., THF)
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (KF)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.