Description

3'-Hydroxy-3',5'-Diepidaunorubicin is a structurally modified derivative of the anthracycline antibiotic daunorubicin, characterized by the presence of additional hydroxyl and epoxide functional groups. This compound is of significant interest in pharmaceutical research and development, particularly for its potential as a key intermediate or active pharmaceutical ingredient (API) in the synthesis of novel chemotherapeutic agents. It is primarily utilized by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in oncology drug discovery and advanced chemical synthesis.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anthracycline-based anticancer drugs and other therapeutic agents.
• Oncology Research: Used as a reference standard or experimental compound in biochemical and pharmacological studies to investigate mechanisms of action, structure-activity relationships (SAR), and cytotoxicity.
• API Development: Employed in the research and development of new Active Pharmaceutical Ingredients (APIs) targeting various cancer types.
• Chemical Synthesis: Acts as a specialized starting material or intermediate for organic chemists developing complex molecular architectures with potential biological activity.
• Bioconjugation Studies: May be used in the development of antibody-drug conjugates (ADCs) or other targeted drug delivery systems.

Basic Information

Product Name	3'-Hydroxy-3',5'-Diepidaunorubicin
CAS No.	98103-13-0
Molecular Formula	C27H29NO11
Molecular Weight	543.52 g/mol
Synonyms	3'-Hydroxy-3',5'-diepidaunomycin; 3'-Hydroxy-3',5'-diepidaunorubicinol; Daunorubicin derivative, 3'-hydroxy-3',5'-diepi-; (1S,3S)-3-Glycoloyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxo-1-naphthacenyl 3-amino-2,3,6-trideoxy-α-L-lyxo-hexopyranoside; 3'-OH-3',5'-diepidaunorubicin
EINECS	Contact for details

Quality Control

Our 3'-Hydroxy-3',5'-Diepidaunorubicin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by spectroscopic methods (IR, NMR), and residual solvent analysis to ensure it meets the stringent requirements for research and pharmaceutical development. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.