Description

Pamam Dendrimer, Generation 2 Solution CAS NO 93376-66-0 is a precisely engineered, monodisperse hyperbranched polymer solution, representing a key building block in nanotechnology and advanced materials science. Its unique, well-defined three-dimensional architecture with abundant surface amine groups provides exceptional value for creating functionalized platforms and controlled delivery systems. This product is essential for researchers and manufacturers in the pharmaceutical, biomedical, and specialty chemical industries seeking to develop next-generation drug delivery vectors, diagnostic agents, and high-performance nanocomposites.

Application

• Drug Delivery & Gene Transfection: Acts as a versatile nanocarrier or vector for the encapsulation and targeted delivery of therapeutic agents, including small molecules, siRNA, and DNA.
• Diagnostic Imaging: Serves as a scaffold for attaching contrast agents (e.g., gadolinium chelates, fluorescent dyes) for enhanced MRI or optical imaging applications.
• Catalyst Support: Provides a high-surface-area, functional platform for immobilizing metal nanoparticles or organocatalysts, improving catalytic efficiency and recyclability.
• Surface Modification & Coatings: Used to modify material surfaces (e.g., sensors, electrodes) to introduce specific chemical functionalities, improve biocompatibility, or create anti-fouling layers.
• Nanocomposite Materials: Incorporated into polymers or resins as a cross-linking agent or nanoscale additive to enhance mechanical strength, thermal stability, or other material properties.
• Sensor Development: Functionalized with specific receptors or ligands for the selective detection of ions, small molecules, or biomolecules in analytical devices.

Basic Information

Product Name	Pamam Dendrimer, Generation 2 Solution
CAS No.	93376-66-0
Molecular Formula	C62H128N26O12
Molecular Weight	1286.86 g/mol
Synonyms	PAMAM Dendrimer, G2; Poly(amidoamine) Dendrimer, Generation 2; Starburst Dendrimer, G2; Dendrimer PAMAM, G2-NH2; PAMAM G2; 2-Aminoethyl-modified PAMAM Dendrimer; PAMAM (NH2)32 Dendrimer; Polypropylenimine tetraamine dendrimer (related class)
EINECS	Contact for details

Quality Control

Our Pamam Dendrimer, Generation 2 Solution is produced under stringent quality management protocols. Each batch undergoes comprehensive analytical characterization to ensure structural integrity, purity, and consistency. Key parameters such as molecular weight distribution (assessed by GPC or MALDI-TOF), amine group quantification, and solvent content are rigorously verified. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all relevant specifications and test results.

Storage

Preserve in a tightly closed container, protected from light. Store at room temperature (15-25°C) or as specified on the label or COA. The solution is light-sensitive (store away from light). For long-term storage, consider inert gas headspace to minimize oxidative degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow solution
Identification (IR)	Conforms to structure
Concentration	10% w/w in Methanol (or as specified)
Assay (Purity, NMR)	≥ 95%
Molecular Weight (MALDI-TOF)	1286.86 ± 10 Da
Primary Amine Groups (Titration)	28 - 32 per molecule
Solvent Content (GC)	Residual solvent meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.