Description

Poly(8-Bromo-2'-Deoxyadenylic Acid) is a synthetic, brominated oligonucleotide analog designed for advanced biochemical and pharmaceutical research. This modified nucleic acid polymer is critical for studying DNA damage, mutagenesis, and the development of novel therapeutic agents and diagnostic probes. It serves as an essential tool for researchers in pharmaceutical development, molecular biology, and academic research who require high-purity, structurally defined nucleotide polymers.

Application

• Biochemical Research: Used as a substrate or model compound in enzymatic studies related to DNA repair mechanisms and polymerase fidelity.
• Pharmaceutical Development: Serves as a key intermediate or reference standard in the discovery of nucleoside-based antiviral or anticancer drugs.
• Molecular Probes: Can be utilized in the synthesis of labeled probes for studying specific nucleic acid interactions or for diagnostic assay development.
• Academic Studies: Employed in university and institutional labs for fundamental research on DNA structure, stability, and the biological effects of halogenated nucleotides.
• Quality Control: Acts as a reference material for analytical method development and validation within quality control laboratories of fine chemical suppliers.

Basic Information

Product Name	Poly(8-Bromo-2'-Deoxyadenylic Acid)
CAS No.	92267-23-7
Molecular Formula	(C10H11BrN5O6P)n
Molecular Weight	Contact for details
Synonyms	Poly(8-Br-dAMP); 8-Bromo-2'-deoxyadenosine 5'-monophosphate polymer; Poly(8-bromodeoxyadenylic acid); 8-Br-dAMP polymer; Brominated polydeoxyadenylic acid; Poly(8-Br-dA); Oligonucleotide, 8-bromo-2'-deoxyadenylic acid residues
EINECS	Contact for details

Quality Control

Our Poly(8-Bromo-2'-Deoxyadenylic Acid) is manufactured under controlled conditions to ensure high batch-to-batch consistency. Each lot undergoes rigorous analytical testing, including purity assessment by HPLC and structural confirmation. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and other relevant parameters is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure the container is sealed tightly after each use to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Moisture Content	≤ 5.0%
Bromine Content	Contact for details
Average Molecular Weight	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.