Description

4-Bromobenzylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry for the formation of carbon-carbon bonds. Its primary value lies in its ability to introduce the 4-bromobenzyl group into a wide range of electrophiles, enabling the synthesis of complex intermediates for advanced materials and pharmaceuticals. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity building blocks for drug discovery and fine chemical production.

Application

• Key intermediate in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates.
• Building block for liquid crystal materials and organic electronic compounds.
• Used in coupling reactions (e.g., Kumada, Negishi) to create biaryl structures.
• Precursor for ligands in catalysis and advanced polymer synthesis.
• Essential reagent in academic and industrial R&D laboratories for method development.
• Used in the production of agrochemicals and crop protection agents.

Basic Information

Product Name	4-Bromobenzylmagnesium Bromide
CAS No.	92206-72-9
Molecular Formula	C7H6Br2Mg
Molecular Weight	274.23 g/mol
Synonyms	(4-Bromophenyl)methylmagnesium bromide; p-Bromobenzylmagnesium bromide; 1-(Bromomagnesio)methyl-4-bromobenzene; 4-Bromobenzyl Grignard Reagent; (4-Bromobenzyl)magnesium bromide; Magnesium, bromo[(4-bromophenyl)methyl]-; 4-Br-BnMgBr
EINECS	Contact for details

Quality Control

Our 4-Bromobenzylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, concentration, and impurity profiles. We adhere to cGMP standards where applicable, and our quality management system is designed to meet the rigorous demands of pharmaceutical and fine chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly reactive and moisture-sensitive nature, this product must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for extended stability. The container should be kept in a cool, dry, and well-ventilated area, away from incompatible materials.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Water Content (Karl Fischer)	≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.