Description

o-Tolylmagnesium Bromide is a versatile organometallic reagent, specifically an aryl Grignard reagent, widely used in organic synthesis. Its primary value lies in its ability to act as a powerful nucleophile for the formation of new carbon-carbon bonds, enabling the construction of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries, where it is employed in the synthesis of active pharmaceutical ingredients (APIs), fine chemicals, and specialty polymers.

Application

• Pharmaceutical Intermediates: Key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents.
• Fine Chemical Manufacturing: Essential for creating specialty chemicals, dyes, and pigments.
• Material Science Research: Employed in the development of novel polymers, liquid crystals, and organic electronic materials.
• Cross-Coupling Reactions: Acts as a coupling partner in reactions such as Kumada, Negishi, and other transition metal-catalyzed processes.
• Nucleophilic Addition: Used for the addition to carbonyl groups (aldehydes, ketones, esters) to form secondary and tertiary alcohols.
• Academic & R&D Laboratories: A fundamental reagent for methodological development and exploratory organic synthesis.

Basic Information

Product Name	o-Tolylmagnesium Bromide
CAS No.	932-31-0
Molecular Formula	C7H7BrMg
Molecular Weight	195.34 g/mol
Synonyms	2-Methylphenylmagnesium Bromide; (2-Methylphenyl)magnesium Bromide; o-Tolylmagnesium Bromide Solution; Magnesium, bromo(2-methylphenyl)-; Grignard Reagent o-TolylMgBr; Bromo(2-methylphenyl)magnesium; o-Tolyl MgBr; 2-Tolylmagnesium Bromide
EINECS	Contact for details

Quality Control

Our o-Tolylmagnesium Bromide is produced under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm concentration, purity, and suitability for sensitive synthetic applications. A comprehensive Certificate of Analysis (COA) detailing assay (by titration), solvent content, and other critical parameters is provided with every shipment. We adhere to cGMP principles where applicable to support our customers in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile and moisture-sensitive (hygroscopic) nature, this product must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For extended stability, storage at 2-8°C is recommended. Keep away from heat, sparks, open flames, and strong oxidizers.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in solvent)	Typically 0.5M - 2.0M in THF or Diethyl Ether
Assay (Titration)	≥ 95%
Identification (IR)	Conforms to structure
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.