Description

Isobutylmagnesium Bromide is a highly reactive Grignard reagent, a cornerstone organometallic compound in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the synthesis of complex molecules. This reagent is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries, where it is used to introduce the isobutyl group into target structures.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing carbon skeletons in active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of herbicides, fungicides, and other crop protection agents.
• Fine Chemical Manufacturing: Employed in the production of specialty chemicals, flavors, and fragrances.
• Polymer Chemistry: Acts as an initiator or chain transfer agent in the synthesis of specialized polymers.
• Academic & Industrial R&D: A fundamental tool for method development and novel compound synthesis in laboratory settings.
• Nucleophilic Addition Reactions: Specifically for addition to carbonyl compounds (aldehydes, ketones, esters) to form secondary and tertiary alcohols.

Basic Information

Product Name	Isobutylmagnesium Bromide
CAS No.	926-62-5
Molecular Formula	C4H9BrMg
Molecular Weight	161.32 g/mol
Synonyms	Isobutylmagnesium bromide solution; Magnesium, bromo(2-methylpropyl)-; (2-Methylpropyl)magnesium bromide; Iso-BuMgBr; Grignard reagent, isobutylmagnesium bromide
EINECS	Contact for details

Quality Control

Our Isobutylmagnesium Bromide solutions undergo rigorous quality testing to ensure batch-to-batch consistency and reactivity. Quality is assured through analytical methods including titration for assay determination and GC analysis for solvent purity. A Certificate of Analysis (COA) detailing concentration, solvent, and impurity profile is provided with each shipment to support your quality management systems.

Storage

Preserve in a tightly closed container, protected from light. This product is hygroscopic (moisture-sensitive) and highly volatile. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated area. Recommended storage temperature is 2-8°C for extended stability. Keep away from heat, sparks, open flames, and incompatible materials such as water, acids, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to light yellow solution
Concentration (in specified solvent)	Typically 1.0M or 2.0M in diethyl ether or THF
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms to structure
Solvent (GC)	As specified (e.g., Diethyl ether or Tetrahydrofuran)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.