Description

3-((n-Biotinyl-3-Aminopropoxy(Ethoxy)Ethoxy)Ethoxy)-1-o-(Dimethoxytrityl)Propane-1,2-Diol is a sophisticated, multifunctional chemical building block designed for advanced bioconjugation and oligonucleotide synthesis. This compound is engineered to provide a critical link between biotinylated probes and solid-phase synthesis platforms, enabling the creation of highly specific diagnostic and research tools. It is essential for researchers and manufacturers in the fields of molecular diagnostics, next-generation sequencing (NGS), and targeted drug delivery systems who require reliable, high-purity intermediates for probe and linker development.

Application

• Oligonucleotide Synthesis: Serves as a key phosphoramidite precursor for the solid-phase synthesis of biotin-labeled DNA/RNA probes and primers.
• Diagnostic Assay Development: Used to manufacture capture probes and detection elements for ELISA, microarray, and lateral flow assays.
• Next-Generation Sequencing (NGS): Integral for preparing biotinylated adapters and library construction reagents for target enrichment and sequencing workflows.
• Affinity Purification Systems: Enables the synthesis of ligands for streptavidin/avidin-based purification of biomolecules.
• Drug Delivery Conjugates: Acts as a specialized linker in the development of biotin-drug conjugates for targeted therapeutic applications.
• Biomaterial Functionalization: Used to modify surfaces (e.g., nanoparticles, chips) with biotin groups for biosensor and lab-on-a-chip technologies.

Basic Information

Product Name	3-((n-Biotinyl-3-Aminopropoxy(Ethoxy)Ethoxy)Ethoxy)-1-o-(Dimethoxytrityl)Propane-1,2-Diol
CAS No.	869354-57-4
Molecular Formula	C46H67N3O13S
Molecular Weight	902.11 g/mol
Synonyms	1-O-Dimethoxytrityl-3-((N-biotinyl-3-aminopropoxy(Ethoxy)Ethoxy)Ethoxy)Propane-1,2-Diol; DMT-PEG3-Biotin; Biotin-PEG3-DMT Alcohol; 5'-O-(4,4'-Dimethoxytrityl)-N-biotinyl-3,6,9-trioxaundecanediol; Biotinylated DMT-Protected PEG Linker; Biotin-PEG3-DMT; DMT-Biotin-PEG3-OH; Biotin Triethylene Glycol DMT Ether
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to stringent quality protocols under an ISO-certified quality management system. Every batch is characterized by advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural integrity and purity. A comprehensive Certificate of Analysis (COA) detailing identity, assay, and impurity profiles is provided with each shipment to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This material is hygroscopic (moisture-sensitive). Allow the sealed container to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.