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n-(O16-(Dimethoxytrityl)-15-Hydroxy-4,7,10,13-Tetraoxa-Hexadecyl)-2,4-Dinitroaniline CAS NO 869308-41-8


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CAS No.:869308-41-8

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

n-(O16-(Dimethoxytrityl)-15-Hydroxy-4,7,10,13-Tetraoxa-Hexadecyl)-2,4-Dinitroaniline is a sophisticated, multi-functional chemical building block designed for advanced synthesis. This compound is engineered to provide a protected hydroxyl group and a reactive aniline derivative, making it a critical intermediate in the development of complex molecular architectures. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and oligonucleotide synthesis sectors for constructing targeted drug delivery systems, diagnostic probes, and specialized polymers.

Application

  • Oligonucleotide and Peptide Synthesis: Serves as a key protected intermediate for introducing functionalized linkers or labels into nucleic acid and peptide chains.
  • Bioconjugation Chemistry: Used to create stable linkages between biomolecules (e.g., antibodies, proteins) and other entities like drugs, dyes, or solid supports.
  • Polymer Chemistry: Acts as a monomer or functionalization agent for synthesizing specialty polymers with tailored solubility and reactivity profiles.
  • Drug Discovery & Development: Employed in the research and synthesis of novel active pharmaceutical ingredients (APIs) and prodrugs requiring specific solubilizing or targeting moieties.
  • Diagnostic Reagent Manufacturing: Integral in the production of labeled probes and assay components for molecular diagnostics and imaging.
  • Material Science Research: Used to develop novel surface coatings and functional materials with precise chemical properties.

Basic Information

Item Detail
Product Name n-(O16-(Dimethoxytrityl)-15-Hydroxy-4,7,10,13-Tetraoxa-Hexadecyl)-2,4-Dinitroaniline
CAS No. 869308-41-8
Molecular Formula C45H57N3O13
Molecular Weight 847.96 g/mol
Synonyms DMTr-PEG4-2,4-Dinitroaniline; 2,4-Dinitro-N-[15-hydroxy-4,7,10,13-tetraoxa-16-[[(4-methoxyphenyl)diphenylmethyl]oxy]hexadecyl]aniline; 4,7,10,13-Tetraoxa-16-[(4,4'-dimethoxytrityl)oxy]hexadecan-1-amine, N-(2,4-dinitrophenyl) derivative; DMT-PEG4-NH-DNP; Amino-PEG4-DMT Dinitroaniline Derivative; Hydrophilic Spacer Arm Reagent; Protected Polyethylene Glycol Linker
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Quality Control

Our n-(O16-(Dimethoxytrityl)-15-Hydroxy-4,7,10,13-Tetraoxa-Hexadecyl)-2,4-Dinitroaniline is produced under strict quality management protocols to ensure high purity and batch-to-batch consistency, critical for sensitive research and GMP-grade manufacturing. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality systems support compliance with relevant ISO and ICH guidelines for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions or a dry inert atmosphere to maintain stability. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item Specification
Appearance Yellow to orange solid or viscous oil
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Purity (HPLC) ≥ 95% (Area %)
Water Content (KF) ≤ 1.0%
Solvent Residue (GC) Meets ICH limits

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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