Description

3-(1,3-Dioxan-2-Yl)Phenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, used for the formation of carbon-carbon bonds in complex organic synthesis. Its core value lies in enabling the precise introduction of the 3-(1,3-dioxan-2-yl)phenyl moiety, a protected form of a benzaldehyde derivative, into target molecules. This compound is essential for researchers and process chemists in the pharmaceutical and advanced materials sectors who require high-purity intermediates for developing active pharmaceutical ingredients (APIs) and specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for constructing complex molecular scaffolds in the research and development of new therapeutic agents.
• Fine Chemical Production: Used in the synthesis of specialty chemicals, ligands, and catalysts requiring the specific aromatic functionality it provides.
• Material Science Research: Employed in the creation of novel organic electronic materials, polymers, and liquid crystals where controlled aromatic substitution is critical.
• Agrochemical Development: Serves as a precursor in the synthesis of advanced crop protection agents and herbicides.
• Academic & Industrial R&D: A vital tool for methodological development in organic chemistry and scale-up process optimization.

Basic Information

Product Name	3-(1,3-Dioxan-2-Yl)Phenylmagnesium Bromide
CAS No.	849354-21-8
Molecular Formula	C12H15BrMgO2
Molecular Weight	295.45 g/mol
Synonyms	[3-(1,3-Dioxan-2-yl)phenyl]magnesium bromide; 2-[3-(Bromomagnesio)phenyl]-1,3-dioxane; 3-(1,3-Dioxan-2-yl)phenylmagnesium bromide solution; 3-(2,2-Dimethyl-1,3-dioxan-4-yl)phenylmagnesium bromide (related protected form); m-(1,3-Dioxan-2-yl)phenylmagnesium bromide; Grignard Reagent of 3-(1,3-Dioxan-2-yl)bromobenzene; (3-(1,3-Dioxan-2-yl)phenyl)magnesium bromide
EINECS	Contact for details

Quality Control

Our 3-(1,3-Dioxan-2-Yl)Phenylmagnesium Bromide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent composition, to ensure consistency and reliability for sensitive synthetic applications. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting compliance with cGMP and ISO standards where required.

Storage

Preserve in a tightly closed container, protected from light. This material is strictly light-sensitive, easily oxidized, and highly volatile. It must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures, typically between 2°C and 8°C for solutions, or as specified on the label. Keep the container in a cool, dry, well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light yellow
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom)
Assay (by Titration)	≥ 95% (as Grignard reagent)
Purity (GC/HPLC)	Contact for details
Solvent	Specified (Tetrahydrofuran, Diethyl ether)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.