Description

3,3'-Dimethoxy-4''-Methyltrityl Alcohol is a specialized trityl-protected alcohol derivative, a crucial intermediate in advanced organic synthesis. Its primary value lies in its role as a protecting group for hydroxyl functions, particularly in the synthesis of complex, sensitive molecules where selective deprotection is required. This compound is essential for researchers and manufacturers in the pharmaceutical and fine chemical industries, enabling the development of novel active pharmaceutical ingredients (APIs) and nucleotide analogs.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of complex drug candidates and nucleotide-based therapeutics.
• Oligonucleotide Synthesis: Used as a protecting group reagent for hydroxyl functions during solid-phase phosphoramidite synthesis of DNA/RNA fragments.
• Fine Chemical Synthesis: Enables selective protection and deprotection strategies in the production of specialty chemicals and advanced materials.
• Process Research & Development (R&D): A valuable tool for chemists developing new synthetic routes in academic and industrial R&D laboratories.
• Glycosylation Chemistry: Facilitates the synthesis of complex carbohydrate structures and glycosides by protecting specific hydroxyl sites.
• Peptide Chemistry: Can be employed in the synthesis of peptide derivatives where selective side-chain protection is necessary.

Basic Information

Product Name	3,3'-Dimethoxy-4''-Methyltrityl Alcohol
CAS No.	845790-61-6
Molecular Formula	C23H24O3
Molecular Weight	348.44 g/mol
Synonyms	4''-Methyl-3,3'-dimethoxytrityl alcohol; DMT-MMT-OH; 3,3'-Dimethoxy-4'-methyltrityl alcohol; (4-Methylphenyl)bis(4-methoxyphenyl)methanol; MMTr-OH; 4-Methyl-4',4''-dimethoxytrityl alcohol; 4-Methyl-DMT alcohol; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Every batch of 3,3'-Dimethoxy-4''-Methyltrityl Alcohol is manufactured and tested under strict quality management systems. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with high-purity standards for research and synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.