Description

Poly(D(A-Br(5)C).D(G-T)) is a specialized synthetic oligonucleotide polymer. This compound is significant for its role as a high-purity building block in advanced nucleic acid research and therapeutic development. It is essential for researchers and manufacturers in the fields of molecular biology, genetic diagnostics, and oligonucleotide-based pharmaceuticals who require precise and reliable synthetic DNA components.

Application

• Oligonucleotide Synthesis: Serves as a critical monomer or intermediate in the solid-phase synthesis of custom DNA and RNA sequences.
• Antisense & siRNA Therapeutics: Used in the research and development of gene-silencing drugs and therapeutic oligonucleotides.
• Molecular Diagnostics: Acts as a component in the manufacture of probes and primers for PCR, sequencing, and genetic testing kits.
• Biochemical Research: Employed in fundamental studies of nucleic acid structure, function, and protein-nucleic acid interactions.
• CRISPR/Cas9 Systems: Can be utilized in the synthesis of guide RNA (gRNA) components for gene-editing applications.
• DNA Microarray Fabrication: Used as a high-purity raw material for spotting solutions in genomic microarray production.

Basic Information

Product Name	Poly(D(A-Br(5)C).D(G-T))
CAS No.	89919-23-3
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(deoxyadenylyl-(5'→3')-5-bromodeoxycytidylyl-(5'→3')-deoxyguanylyl-(5'→3')-deoxythymidylyl); d(A-Br(5)C).d(G-T) polymer; Brominated DNA polymer; Synthetic oligonucleotide polymer 89919-23-3; Poly[d(A-Br5C)].poly[d(G-T)]; DNA copolymer containing 5-bromocytosine
EINECS	Contact for details

Quality Control

Our Poly(D(A-Br(5)C).D(G-T)) is manufactured under stringent controls to ensure the high purity and consistency required for sensitive life science applications. Each batch is analyzed using advanced techniques such as HPLC, mass spectrometry, and capillary electrophoresis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container should be kept in a desiccated environment. For long-term stability, consider storage at -20°C under inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Purity (HPLC)	≥ 95%
Assay (UV)	90 - 110%
Water Content (KF)	≤ 5.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.