Description

5-Bromo-2-Deoxycytidine 5-Monophosphate Sodium is a modified nucleoside monophosphate crucial for advanced biochemical research and pharmaceutical development. This compound serves as a vital building block in oligonucleotide synthesis, enabling the study of DNA structure, function, and therapeutic modulation. It is primarily utilized by researchers and manufacturers in the fields of antiviral drug discovery, molecular biology, and diagnostic probe development.

Application

• Oligonucleotide Synthesis: A key phosphoramidite precursor for incorporating brominated cytosine analogs into synthetic DNA and RNA strands.
• Antiviral Research: Investigated as a potential metabolite or prodrug in the development of nucleoside analog-based antiviral therapies.
• Biochemical Studies: Used to probe enzyme mechanisms, particularly those of DNA polymerases and kinases, due to its halogenated base.
• Diagnostic Development: Employed in the creation of labeled probes for genetic testing, hybridization assays, and next-generation sequencing applications.
• Structural Biology: Facilitates X-ray crystallography and NMR studies of nucleic acid interactions by acting as a heavy-atom derivative.
• Cancer Research: Explored for its potential to inhibit DNA synthesis or repair pathways in targeted oncology research.

Basic Information

Product Name	5-Bromo-2-Deoxycytidine 5-Monophosphate Sodium
CAS No.	88188-03-8
Molecular Formula	C9H12BrN3NaO7P
Molecular Weight	408.08 g/mol
Synonyms	5-Bromo-2'-deoxycytidine 5'-monophosphate sodium salt; 5-Br-dCMP sodium; Sodium 5-bromo-2'-deoxycytidine 5'-monophosphate; 5-Bromo-2'-deoxycytidine 5'-(disodium phosphate); 5-Bromodeoxycytidine monophosphate sodium; BrdCMP Na; 5-Bromo-dCMP Na
EINECS	Contact for details

Quality Control

Our 5-Bromo-2-Deoxycytidine 5-Monophosphate Sodium is produced under stringent conditions to ensure high purity and batch-to-batch consistency, suitable for sensitive research applications. Each lot undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. Allow the sealed container to equilibrate to room temperature before opening to prevent moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Heavy Metals	≤ 20 ppm
Solubility	Soluble in water, slightly soluble in methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.