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3-(2,5,5-Trimethyl-1,3-Dioxan-2-Yl)Propylmagnesium Chloride CAS NO 88128-60-3


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CAS No.:88128-60-3

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-(2,5,5-Trimethyl-1,3-Dioxan-2-Yl)Propylmagnesium Chloride is a highly reactive Grignard reagent, a critical organometallic intermediate for constructing complex molecular frameworks. Its value lies in enabling precise carbon-carbon bond formation, essential for synthesizing specialty chemicals and advanced materials. This compound is primarily needed by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for developing novel active ingredients and high-value intermediates.

Application

  • Pharmaceutical Intermediate Synthesis: Key building block for introducing the functionalized propyl-dioxane moiety into target molecules during the development of new drug candidates.
  • Agrochemical Active Ingredient Production: Used in the synthesis of advanced herbicides, fungicides, and insecticides that require specific sterically hindered structures.
  • Fine Chemical and Fragrance Manufacturing: Enables the creation of complex, high-purity aroma chemicals and specialty esters with unique olfactory properties.
  • Material Science Research: Serves as a precursor for modifying polymer chains or surface coatings to impart specific chemical resistance or adhesion properties.
  • Academic and Industrial R&D: A valuable tool for methodological studies in organic synthesis and catalysis for creating novel carbon skeletons.

Basic Information

Item Details
Product Name 3-(2,5,5-Trimethyl-1,3-Dioxan-2-Yl)Propylmagnesium Chloride
CAS No. 88128-60-3
Molecular Formula C12H23ClMgO2
Molecular Weight 258.86 g/mol
Synonyms 2-[3-(Chloromagnesio)propyl]-2,5,5-trimethyl-1,3-dioxane; (3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)propyl)magnesium chloride; Trimethyldioxanylpropylmagnesium Chloride; Grignard Reagent 88128-60-3; 3-(2,5,5-Trimethyl-1,3-dioxan-2-yl)propylmagnesium chloride solution
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Quality Control

Every batch of our 3-(2,5,5-Trimethyl-1,3-Dioxan-2-Yl)Propylmagnesium Chloride is manufactured and handled under strict quality protocols to ensure consistency and reactivity. We provide comprehensive Certificates of Analysis (COA) detailing key parameters such as concentration (typically supplied as a solution in THF or diethyl ether), assay by titration, and impurity profile. Our quality system is designed to meet the stringent requirements of cGMP and ISO standards for advanced chemical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Due to its properties of being highly volatile, easily oxidized, and reactive with strong acids, this material must be stored under an inert atmosphere (argon or nitrogen) at recommended temperatures of 2°C to 8°C. The container should be kept in a cool, dry, well-ventilated area away from incompatible materials such as protic solvents, acids, and oxidizers. Handle and open containers only in a controlled, moisture-free environment.

Specification

Item Specification
Appearance Colorless to pale yellow solution
Identification (IR) Conforms to structure
Assay (Titration) 0.5 M in THF (or as specified)
Purity (GC/HPLC) ≥ 95% (of Grignard reagent)
Water Content (KF) ≤ 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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