Description

Guanosine 5'-(Tetrahydrogen Triphosphate), 2'-Deoxy-, Trilithium Salt is a high-purity nucleotide triphosphate essential for enzymatic and molecular biology research. This compound serves as a critical building block for DNA synthesis, particularly in applications requiring precise biochemical control. It is primarily utilized by biotechnology, pharmaceutical, and diagnostic research sectors for processes such as PCR, DNA sequencing, and enzyme kinetics studies.

Application

• Polymerase Chain Reaction (PCR): Acts as a substrate (dGTP) for DNA polymerases in amplification protocols.
• DNA Sequencing & Synthesis: Used in enzymatic DNA synthesis for next-generation sequencing (NGS) and oligonucleotide production.
• Enzyme Kinetics & Biochemical Assays: Serves as a cofactor or substrate in studies of kinases, polymerases, and other nucleotide-dependent enzymes.
• Diagnostic Kit Manufacturing: A key raw material in the formulation of molecular diagnostic kits and reagents.
• Cell Culture & Virology Research: Employed in studies of viral replication mechanisms and nucleic acid metabolism.
• Pharmaceutical R&D: Used in drug discovery research targeting nucleotide metabolism pathways.

Basic Information

Product Name	Guanosine 5'-(Tetrahydrogen Triphosphate), 2'-Deoxy-, Trilithium Salt
CAS No.	85737-05-9
Molecular Formula	C10H14Li3N5O13P3
Molecular Weight	523.03 g/mol (anhydrous basis)
Synonyms	2'-Deoxyguanosine-5'-triphosphate trilithium salt; dGTP trilithium salt; Deoxyguanosine triphosphate trilithium salt; 2'-Deoxy-GTP Li3; Guanosine, 2'-deoxy-, 5'-(tetrahydrogen triphosphate), trilithium salt; 2'-Deoxyguanosine 5'-triphosphate, Li salt; dGTP, Li3 salt; Deoxyguanosine-5'-triphosphate trilithium
EINECS	Contact for details

Quality Control

Our Guanosine 5'-(Tetrahydrogen Triphosphate), 2'-Deoxy-, Trilithium Salt is manufactured under strict quality systems suitable for research and in-vitro diagnostic use. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure consistency and performance. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This material is hygroscopic (moisture-sensitive). For long-term stability, store desiccated. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay (Enzymatic)	≥ 90%
pH (1% Solution)	6.0 - 8.0
Water Content (KF)	≤ 5.0%
Endotoxin (LAL)	< 10 EU/mg
Filter Sterilization	Passes through 0.2 µm filter

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.