Description

1-Methyl-1-Propenylmagnesium Bromide is a highly reactive organomagnesium reagent, specifically a Grignard reagent, widely utilized in synthetic organic chemistry. Its primary value lies in its ability to act as a powerful nucleophile and carbon nucleophile source for the formation of new carbon-carbon bonds, enabling the synthesis of complex molecular architectures. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors, where it is used to introduce the 1-methyl-1-propenyl functional group into target molecules.

Application

• Pharmaceutical Intermediate Synthesis: A key building block for introducing the tert-butylvinyl group into active pharmaceutical ingredients (APIs) and drug candidates.
• Agrochemical Manufacturing: Used in the production of advanced pesticides and herbicides, where its unique carbon skeleton contributes to biological activity.
• Fine Chemical Production: Serves as a versatile reagent for the synthesis of specialty chemicals, flavors, and fragrances.
• Polymer & Material Science: Employed in the creation of novel monomers and functional polymers with tailored properties.
• Academic & R&D Laboratories: A critical tool for methodological development and exploratory synthesis in organic chemistry research.
• Cross-Coupling Reactions: Acts as an effective coupling partner in transition metal-catalyzed reactions, such as Kumada couplings.

Basic Information

Product Name	1-Methyl-1-Propenylmagnesium Bromide
CAS No.	85676-85-3
Molecular Formula	C4H7BrMg
Molecular Weight	159.31 g/mol
Synonyms	1-Methylprop-1-en-1-ylmagnesium bromide; (1-Methyl-1-propenyl)magnesium bromide; 2-Buten-2-ylmagnesium bromide; tert-Butylvinylmagnesium bromide; Isobutenylmagnesium bromide; Magnesium, bromo(1-methyl-1-propenyl)-; Grignard reagent C4H7BrMg
EINECS	Contact for details

Quality Control

Our 1-Methyl-1-Propenylmagnesium Bromide is manufactured under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for Grignard concentration and GC analysis for purity and solvent content, to ensure consistency and reliability for your synthetic applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. This material is hygroscopic (moisture-sensitive) and must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. For optimal stability, maintain at room temperature (15-25°C). Keep away from moisture, heat, and incompatible materials such as acids, oxidizers, and protic solvents.

Specification

Item	Specification
Appearance	Clear, colorless to light yellow solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Customizable)
Assay (Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Water Content (Karl Fischer)	< 100 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.