Description

Polythymidylic Acid Sodium Salt is a synthetic oligonucleotide polymer composed of deoxythymidine monophosphate units. This compound serves as a critical research tool and a fundamental building block in molecular biology and nucleic acid chemistry. It is essential for scientists and manufacturers in the biotechnology, pharmaceutical, and diagnostic sectors who require high-purity nucleic acid components for applications ranging from primer synthesis to hybridization studies.

Application

• Molecular Biology Research: Used as a homopolymer template or primer in enzymatic reactions, including reverse transcription and polymerase chain reaction (PCR).
• Nucleic Acid Synthesis: Acts as a starting material or intermediate in the solid-phase synthesis of oligonucleotides and more complex DNA constructs.
• Hybridization Studies: Employed in model systems to study the kinetics and thermodynamics of DNA-DNA and DNA-RNA duplex formation.
• Biochemical Reagent: Serves as a substrate for enzymes such as nucleases, polymerases, and phosphatases in activity assays.
• Diagnostic Development: Utilized in the design and calibration of diagnostic assays and biosensors that rely on nucleic acid detection.
• Pharmaceutical Research: Investigated for use in antisense oligonucleotide development, gene therapy vectors, and other therapeutic nucleic acid platforms.

Basic Information

Product Name	Polythymidylic Acid Sodium Salt
CAS No.	85597-60-0
Molecular Formula	(C10H13N2NaO8P)n
Molecular Weight	Contact for details
Synonyms	Poly(dT) Sodium Salt; Polydeoxythymidylic Acid Sodium Salt; Polythymidylic Acid, Sodium Salt; dT Homopolymer Sodium Salt; Poly(dT); Poly T; Oligo(dT) Sodium Salt (for shorter chains); Polydeoxythymidylate Sodium Salt
EINECS	Contact for details

Quality Control

Our Polythymidylic Acid Sodium Salt is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, spectroscopy for structural confirmation, and tests for moisture and endotoxin levels where applicable. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment. Allow the vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (UV/VIS)	Complies
Identification (IR)	Complies
Assay (HPLC)	≥ 95% (Polymer Content)
Chain Length (Average)	Contact for details
Moisture Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin	< 10 EU/mg (if specified)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.