Description

2',3'-Dideoxyguanosine 5'-Diphosphate is a modified nucleoside diphosphate analog, a critical biochemical building block for research and development. This compound is essential for studying DNA/RNA synthesis inhibition, viral replication mechanisms, and nucleotide metabolism pathways. It is primarily utilized by researchers and manufacturers in the fields of antiviral drug discovery, molecular biology, and biochemical assay development.

Application

• Biochemical Research: Substrate or inhibitor in enzymatic studies of DNA polymerases and reverse transcriptases.
• Antiviral Drug Development: Key intermediate in the synthesis and evaluation of nucleoside analog prodrugs targeting viral infections.
• Molecular Biology: Used in the study of nucleotide incorporation and chain termination mechanisms.
• Diagnostic Reagent Manufacturing: Component in kits for enzymatic assays and metabolic pathway analysis.
• Academic Research: Tool compound for investigating cellular biochemistry and pharmacology of nucleotide analogs.

Basic Information

Product Name	2',3'-Dideoxyguanosine 5'-Diphosphate
CAS No.	84328-12-1
Molecular Formula	C10H14N5O10P2
Molecular Weight	425.20 g/mol
Synonyms	ddGDP; 2',3'-Dideoxyguanosine-5'-diphosphate; 2',3'-Dideoxy-GDP; Guanosine, 2',3'-dideoxy-, 5'-(trihydrogen diphosphate); 9-[(2,3-Dideoxy-β-D-glycero-pentofuranosyl)oxy]-6-amino-1,9-dihydro-6H-purin-6-one 5'-(trihydrogen diphosphate)
EINECS	Contact for details

Quality Control

Our 2',3'-Dideoxyguanosine 5'-Diphosphate is produced under stringent quality management systems. Each batch undergoes comprehensive analytical testing including HPLC for purity, NMR for structural confirmation, and mass spectrometry for identity verification. Certificates of Analysis (COA) detailing all specifications are available upon request to ensure compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a desiccator before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.