Description

Dgtpαs CAS NO 82337-56-2 is a high-purity biochemical reagent used in advanced research and development. This compound is critical for nucleotide synthesis and modification processes, offering researchers a reliable and consistent building block. It is primarily utilized by biotechnology, pharmaceutical, and academic research institutions for applications in molecular biology, enzymology, and drug discovery.

Application

• Nucleotide Synthesis: As a key precursor or modified nucleotide analog in the enzymatic or chemical synthesis of oligonucleotides and nucleic acids.
• Enzymology Studies: Used as a substrate or inhibitor in studies involving polymerases, kinases, and other nucleotide-processing enzymes to understand reaction mechanisms.
• Drug Discovery: Serves as a critical intermediate in the development of antiviral and anticancer nucleoside/nucleotide analog therapeutics.
• Molecular Biology Research: Employed in PCR, sequencing, and site-directed mutagenesis experiments requiring specialized or labeled nucleotides.
• Biochemical Assay Development: Used in the formulation of high-sensitivity diagnostic kits and assays that detect specific enzymatic activities.
• Academic & Industrial R&D: A fundamental reagent for basic research in genetics, epigenetics, and cellular signaling pathways within university and corporate laboratories.

Basic Information

Product Name	Dgtpαs
CAS No.	82337-56-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	2'-Deoxyguanosine-5'-O-(1-thiotriphosphate), S-isomer; 2'-Deoxyguanosine 5'-(α-thio)triphosphate; dGTPαS; Deoxyguanosine 5'-(α-thiotriphosphate); Guanosine 5'-(α-thio)triphosphate, 2'-deoxy-; α-Thio-dGTP; dGTPαS sodium salt; 2'-Deoxy-GTPαS
EINECS	Contact for details

Quality Control

Our Dgtpαs is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity verification, to ensure it meets the high standards required for sensitive research applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 95%
Assay	≥ 90% (Anhydrous basis)
Water Content (KF)	≤ 5%
Solubility	Soluble in water or buffer solution

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.