Description

2-Amino-2'-Deoxyadenosine 5'-Triphosphate is a modified nucleotide triphosphate analog, a critical building block for advanced biochemical research and development. This compound is essential for studying DNA replication, repair mechanisms, and enzyme kinetics where standard nucleotides are insufficient. It is primarily utilized by research institutions, diagnostic developers, and pharmaceutical companies engaged in molecular biology, enzymology, and next-generation sequencing applications.

Application

• Molecular Biology Research: Used as a substrate or inhibitor in enzymatic studies of DNA polymerases, reverse transcriptases, and other nucleic acid-processing enzymes.
• Next-Generation Sequencing (NGS): Serves as a specialized nucleotide for developing novel sequencing-by-synthesis (SBS) platforms and probing enzyme fidelity.
• Diagnostic Assay Development: Incorporated into probes or as a labeled compound for sensitive detection systems in clinical diagnostics.
• Structural Biology: Employed in X-ray crystallography and NMR studies to understand enzyme-substrate interactions and catalytic mechanisms.
• Antiviral & Anticancer Research: Investigated for its potential as a chain terminator or modulator in the development of nucleoside analog therapeutics.
• Biochemical Tool Development: Key reagent for creating labeled nucleotides, affinity probes, and other tools for studying nucleic acid metabolism.

Basic Information

Product Name	2-Amino-2'-Deoxyadenosine 5'-Triphosphate
CAS No.	81503-63-1
Molecular Formula	C10H16N6O12P3
Molecular Weight	529.17 g/mol
Synonyms	2-Amino-dATP; 2-NH2-dATP; 2-Amino-2'-deoxyadenosine-5'-triphosphate; 2-Aminodeoxyadenosine triphosphate; 2-Amino-2'-deoxy-ATP; dATP-NH2; 2-Amino-2'-deoxyadenosine triphosphate
EINECS	Contact for details

Quality Control

Our 2-Amino-2'-Deoxyadenosine 5'-Triphosphate is manufactured under stringent conditions to ensure high purity and batch-to-batch consistency suitable for sensitive research applications. Quality is verified through comprehensive analytical techniques including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a desiccated environment. This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability. For long-term storage, keep under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 3.0%
Solubility	Soluble in water, buffer solutions

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.