Description

Oligo(Dg-Dc) CAS NO 80458-01-1 is a synthetic oligonucleotide composed of alternating deoxyguanosine (dG) and deoxycytidine (dC) bases. This specific sequence is a critical reagent in molecular biology research, particularly for studying DNA-protein interactions and nucleic acid structure. It is essential for researchers and manufacturers in the biotechnology, pharmaceutical, and diagnostic sectors who require high-purity, sequence-defined oligonucleotides for applications such as probe development and binding studies.

Application

• Molecular Biology Research: Used as a specific probe or primer in polymerase chain reaction (PCR) and other amplification techniques.
• DNA-Protein Interaction Studies: Serves as a binding substrate for proteins like transcription factors, zinc finger proteins, and other DNA-binding domains.
• Nucleic Acid Structure Analysis: Employed in biophysical studies to investigate the properties of double-stranded DNA, including stability and conformation.
• Diagnostic Assay Development: Acts as a key component in the design and validation of diagnostic kits for genetic testing and pathogen detection.
• Biopharmaceutical R&D: Utilized in drug discovery pipelines targeting genetic pathways, including antisense and gene silencing research.
• Quality Control Standard: Functions as a reference material for calibrating instruments and validating methods in analytical laboratories.

Basic Information

Product Name	Oligo(Dg-Dc) CAS NO 80458-01-1
CAS No.	80458-01-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Poly(dG-dC); Poly(deoxyguanylic-deoxycytidylic) acid; Alternating dG-dC oligonucleotide; dG-dC polymer; Oligo(dG-dC); Oligodeoxyribonucleotide (dG-dC)n; DNA oligonucleotide (dG-dC); Synthetic dG-dC sequence
EINECS	Contact for details

Quality Control

Our Oligo(Dg-Dc) is manufactured under stringent conditions to ensure the highest standards of purity and sequence fidelity. Each batch undergoes comprehensive analytical testing, including HPLC for purity assessment, mass spectrometry (MS) for identity confirmation, and absorbance measurements for accurate quantification. Certificates of Analysis (COA) detailing all specifications and test results are provided to guarantee reproducible performance in your critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a non-frost-free freezer for long-term stability. This product is hygroscopic (moisture-sensitive). Allow the vial to reach room temperature before opening to prevent condensation and degradation. For best results, prepare working aliquots to avoid repeated freeze-thaw cycles.

Specification

Item	Specification
Appearance	White to off-white solid or lyophilized powder
Identification (HPLC/MS)	Conforms to standard
Purity (HPLC)	≥ 95%
Assay (UV)	≥ 85%
Extinction Coefficient	Provided on COA
Molecular Weight	As specified per order (Theoretical)
Endotoxin Level	< 10 EU/mg (for molecular biology grade)
Solubility	Soluble in TE buffer or nuclease-free water

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.