Description

Pentafluorophenylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, with the CAS number 879-05-0. Its core value lies in its ability to efficiently introduce the electron-deficient pentafluorophenyl group into target molecules, a critical transformation for modifying material properties and biological activity. This compound is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials sectors who require precise fluorinated building blocks.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing fluorinated aromatic cores in active pharmaceutical ingredients (APIs), enhancing metabolic stability and lipophilicity.
• Agrochemical Development: Used to synthesize novel fluorinated pesticides and herbicides, where the pentafluorophenyl group can improve efficacy and environmental profile.
• Liquid Crystal & OLED Material Production: Serves as a precursor for fluorinated compounds used in electronic displays and organic light-emitting diodes to optimize performance.
• Polymer & Specialty Chemical Modification: Employed to graft pentafluorophenyl groups onto polymers or small molecules, altering surface properties, solubility, and chemical resistance.
• Catalyst Ligand Preparation: Facilitates the synthesis of sophisticated fluorinated ligands for transition metal catalysis.
• Academic & R&D Laboratories: A fundamental tool for exploring new synthetic methodologies and creating fluorinated molecular libraries for screening.

Basic Information

Item	Detail
Product Name	Pentafluorophenylmagnesium Bromide
CAS No.	879-05-0
Molecular Formula	C6F5MgBr
Molecular Weight	263.22 g/mol
Synonyms	Magnesium, bromopentafluorophenyl-; Pentafluorophenylmagnesium bromide solution; (Pentafluorophenyl)magnesium bromide; Grignard reagent C6F5MgBr; Bromo(pentafluorophenyl)magnesium; 2,3,4,5,6-Pentafluorophenylmagnesium bromide
EINECS	Contact for details

Quality Control

Our Pentafluorophenylmagnesium Bromide is manufactured under stringent controls to ensure batch-to-batch consistency and high reactivity. Quality is verified through analytical techniques including titration and GC/HPLC to confirm concentration and purity in solution. A Certificate of Analysis (COA) detailing specific results is provided with each shipment, and we support compliance with relevant REACH regulations for the global market.

Storage

Preserve in a tightly closed container, protected from light. This material is moisture-sensitive (hygroscopic) and easily oxidized; it must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For solutions, store as recommended on the specific label, typically between 2°C and 8°C. Keep away from strong acids and oxidizing agents.

Specification

Item	Specification
Appearance (Solution)	Clear, colorless to light brown
Concentration (in THF or Ether)	0.5 M - 1.0 M (Custom concentrations available)
Assay (Titration)	≥ 95% (of stated concentration)
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.