Description

1-Hexadecylzinc Bromide is a high-value organozinc reagent, specifically a long-chain alkylzinc halide, with the CAS number 737797-10-3. This compound is a critical intermediate for the efficient introduction of a hexadecyl (cetyl) group into target molecules via cross-coupling reactions, enabling precise carbon-chain elongation. It is essential for researchers and process chemists in the pharmaceutical, advanced materials, and specialty chemical sectors who require reliable, high-purity building blocks for complex synthesis.

Application

• Pharmaceutical Intermediate: Key reagent in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates requiring long alkyl chain motifs.
• Advanced Material Synthesis: Used in the production of liquid crystals, organic semiconductors, and surface-modifying agents where controlled alkylation is crucial.
• Specialty Polymer Chemistry: Serves as an initiator or chain-transfer agent in the development of polymers with specific hydrophobic properties.
• Organic Synthesis & Catalysis: A versatile nucleophile in Negishi and related cross-coupling reactions for C-C bond formation in fine chemical manufacturing.
• Agrochemical Research: Employed in creating novel surfactants, adjuvants, and active compounds with tailored lipophilicity.
• Chemical Biology Probes: Useful for labeling and modifying biomolecules with long hydrophobic chains for research applications.

Basic Information

Product Name	1-Hexadecylzinc Bromide
CAS No.	737797-10-3
Molecular Formula	C₁₆H₃₃BrZn
Molecular Weight	370.73 g/mol
Synonyms	Hexadecylzinc Bromide; Cetylzinc Bromide; Zinc, bromohexadecyl-; Bromo(cetyl)zinc; Bromo(hexadecyl)zinc; 1-Bromohexadecylzinc; C16-Alkylzinc Bromide; n-Hexadecylzinc Bromide
EINECS	Contact for details

Quality Control

Our production of 1-Hexadecylzinc Bromide adheres to stringent quality protocols to ensure batch-to-batch consistency and high reactivity. Each lot is characterized by advanced analytical techniques including NMR, GC, and titration to confirm identity, purity, and active zinc content. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment, supporting your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area. Due to its hygroscopic and moisture-sensitive nature, the reagent should be handled in a dry, inert environment to prevent decomposition. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Zn content)	≥ 95% (by Titration)
Concentration (in solvent)	0.5 M in THF (or as specified)
Purity (GC)	≥ 90% (alkyl chain purity)
Solvent	Specified (e.g., Tetrahydrofuran, Diethyl ether)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.