Description

3'-(4-Morpholinyl)-3'-Deaminodaunorubicin is a synthetic derivative of the anthracycline antibiotic daunorubicin, modified at the 3'-position with a morpholine ring. This structural modification is significant for altering the compound's biological activity, particularly its interaction with DNA and topoisomerase II, making it a valuable intermediate in pharmaceutical research and development. It is primarily utilized by researchers and manufacturers in the life sciences sector for the synthesis of novel chemotherapeutic agents and as a reference standard in biochemical studies.

Application

• Pharmaceutical Intermediate: Key building block in the research and synthesis of novel anthracycline-based anticancer agents.
• Biochemical Research: Used as a reference standard or probe in studies of DNA intercalation, topoisomerase II inhibition, and cellular apoptosis mechanisms.
• Medicinal Chemistry: Serves as a core scaffold for structure-activity relationship (SAR) studies to develop new derivatives with improved efficacy or reduced cardiotoxicity.
• Oncology Drug Discovery: Investigated for its potential as a lead compound in the development of targeted cancer therapies.
• Academic & Institutional Research: Employed in university and institutional labs for fundamental research in cancer biology and pharmacology.

Basic Information

Product Name	3'-(4-Morpholinyl)-3'-Deaminodaunorubicin
CAS No.	79867-78-0
Molecular Formula	C32H37NO11
Molecular Weight	611.64 g/mol
Synonyms	3'-Morpholino-3'-deaminodaunorubicin; 3'-Deamino-3'-(4-morpholinyl)daunorubicin; 3'-Morpholinodaunorubicin; 3'-Deaminodaunorubicin morpholino derivative; Daunorubicin, 3'-deamino-3'-(4-morpholinyl)-; 3'-N-Morpholino-3'-deaminodaunorubicin; 3'-(N-Morpholino)-3'-deaminodaunorubicin; 79867-78-0
EINECS	Contact for details

Quality Control

Our 3'-(4-Morpholinyl)-3'-Deaminodaunorubicin is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay results, and impurity profiles is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	Red to orange-red powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.