Description

Guanosine 5'-(Tetrahydrogen Triphosphate), Dilithium Salt is a high-purity nucleotide essential for biochemical research and pharmaceutical development. This compound serves as a critical substrate and energy source in enzymatic reactions, particularly those involving RNA synthesis and cellular signaling pathways. It is primarily utilized by biotechnology companies, academic research institutions, and pharmaceutical manufacturers engaged in molecular biology, enzymology, and diagnostic assay development.

Application

• Enzymatic Substrate for RNA Polymerases: Essential for in vitro transcription reactions to synthesize RNA molecules for research and therapeutic applications.
• Biochemical Research & Assay Development: Used as a key reagent in kinase activity assays, GTP-binding protein studies, and other signal transduction research.
• Diagnostic Kit Manufacturing: A vital component in the production of kits for molecular diagnostics and next-generation sequencing (NGS) workflows.
• Pharmaceutical Intermediate: Employed in the synthesis and development of nucleotide-based antiviral drugs and other therapeutic agents.
• Cell Culture & Metabolism Studies: Used to study cellular energy metabolism and nucleotide salvage pathways in various cell lines.
• Reference Standard: Serves as a high-purity analytical standard for quality control in pharmaceutical and biotechnology production.

Basic Information

Product Name	Guanosine 5'-(Tetrahydrogen Triphosphate), Dilithium Salt
CAS No.	79787-02-3
Molecular Formula	C10H14Li2N5O14P3
Molecular Weight	523.07 g/mol (anhydrous basis)
Synonyms	Guanosine-5'-triphosphate, Dilithium Salt; GTP, Dilithium Salt; 5'-GTP Li2; Guanosine 5'-triphosphoric acid dilithium salt; Guanine ribonucleoside 5'-(tetrahydrogen triphosphate) dilithium salt; 2-Amino-1,9-dihydro-9-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-6H-purin-6-one 5'-(tetrahydrogen triphosphate) dilithium salt
EINECS	Contact for details

Quality Control

Our Guanosine 5'-(Tetrahydrogen Triphosphate), Dilithium Salt is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for research and pharmaceutical applications. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This material is hygroscopic (moisture-sensitive) and must be kept dry. For long-term storage, desiccate at -20°C. Allow the sealed container to reach room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white powder or solid
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	≥ 95%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 5.0%
pH (1% Solution)	6.0 - 8.0
Endotoxin (LAL)	< 0.1 EU/µmol (Research Grade)
Filter Sterility	Passes 0.2 µm filter (Sterile Grade)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.