Description

Pregna-1,4-Diene-3,20-Dione, 21-(3-Carboxy-1-Oxopropoxy)-11-Hydroxy-16,17-[(1-Methylethylidene)Bis(Oxy)]-, Monosodium Salt, (11Beta,16Alpha)- is a high-purity, complex steroid derivative with significant pharmaceutical relevance. This compound is valued for its role as a key synthetic intermediate or active pharmaceutical ingredient (API) in advanced therapeutic development. It is primarily required by research institutions and pharmaceutical manufacturers engaged in the synthesis of novel corticosteroids and other specialized steroid-based medications.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of potent corticosteroid APIs.
• Active Pharmaceutical Ingredient (API): Potential use as the active moiety in formulated anti-inflammatory or immunosuppressant drugs.
• Biochemical Research: Used in pharmacological studies to investigate steroid receptor interactions and metabolic pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
• Process Development: Employed in scaling up and optimizing synthetic routes for steroid manufacturing.

Basic Information

Product Name	Pregna-1,4-Diene-3,20-Dione, 21-(3-Carboxy-1-Oxopropoxy)-11-Hydroxy-16,17-[(1-Methylethylidene)Bis(Oxy)]-, Monosodium Salt, (11Beta,16Alpha)-
CAS No.	78806-75-4
Molecular Formula	C28H35NaO9
Molecular Weight	538.57 g/mol
Synonyms	Prednisolone 21-Hemisuccinate Sodium Salt; Prednisolone Sodium Succinate (related derivative); 11β,16α,17,21-Tetrahydroxypregna-1,4-diene-3,20-dione 21-Hemisuccinate Sodium Salt; 16α,17-Isopropylidenedioxy-11β-hydroxy-21-succinyloxypregna-1,4-diene-3,20-dione Monosodium Salt; (11β,16α)-21-[(3-Carboxy-1-oxopropoxy)-11-hydroxy-16,17-(1-methylethylidene)bis(oxy)]-pregna-1,4-diene-3,20-dione Monosodium Salt; Soluble Prednisolone Derivative; Sodium Prednisolone Succinate Analog; PDS Na Salt.
EINECS	Contact for details

Quality Control

Our Pregna-1,4-Diene-3,20-Dione derivative is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation, to ensure it meets stringent specifications for pharmaceutical use. Certificates of Analysis (COA) detailing all test results are provided and can be tailored to support regulatory filings (e.g., DMF, CEP). We adhere to cGMP guidelines where applicable to guarantee supply chain integrity and product traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term storage, consider desiccated conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.