Description

Dexamethasone Sodium Phosphate is a highly potent synthetic glucocorticoid corticosteroid, widely recognized for its anti-inflammatory and immunosuppressive properties. This water-soluble phosphate ester salt of dexamethasone is a critical active pharmaceutical ingredient (API) for formulating injectable and ophthalmic solutions. It is essential for manufacturers in the pharmaceutical and veterinary medicine industries requiring a reliable, high-purity compound for producing treatments for severe allergic reactions, inflammatory conditions, and certain cancers.

Application

• Pharmaceutical API: Primary use as the active ingredient in injectable formulations for emergency treatment of severe inflammation, allergic reactions, and cerebral edema.
• Ophthalmic Solutions: Key component in eye drops and ointments for treating inflammatory eye conditions such as uveitis and allergic conjunctivitis.
• Veterinary Medicine: Used in anti-inflammatory and immunosuppressive therapies for companion animals and livestock.
• Research & Development: Vital reference standard and biochemical tool in pharmacological and immunological research studies.
• Hospital Compounding: Utilized in pharmacy compounding for preparing customized dosage forms not commercially available.

Basic Information

Product Name	Dexamethasone Sodium Phosphate
CAS No.	55203-24-2
Molecular Formula	C22H28FNa2O8P
Molecular Weight	516.39 g/mol
Synonyms	Dexamethasone 21-Phosphate Disodium Salt; Dexamethasone Phosphate Sodium; Dexamethasone Sodium Phosphate; 9α-Fluoro-16α-methylprednisolone 21-phosphate disodium salt; Dexamethasone Disodium Phosphate; Dexamethasone 21-(Disodium Phosphate); Oradexon; Decadron Phosphate; Dexasone
EINECS	259-552-6

Quality Control

Our Dexamethasone Sodium Phosphate is manufactured under strict quality management systems. It is typically tested to meet or exceed relevant pharmacopeial standards such as USP, EP, and BP. Every batch undergoes comprehensive analytical testing including identification, assay, impurity profiling, and residual solvent analysis to ensure high purity and consistent performance. A Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to prevent degradation. For long-term stability, consider storage under inert atmosphere.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 8.0%
pH (5% solution)	7.5 - 9.0
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 2.0%
Residual Solvents (GC)	Complies with ICH guidelines
Bacterial Endotoxins	< 0.17 EU/mg (if for injectable use)
Sterility (if required)	Passes test

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.