Description

(11Beta,16Alpha)-9-Fluoro-11-Hydroxy-17,21-[(1-Methoxypentylidene)Bis(Oxy)]-16-Methylpregna-1,4-Diene-3,20-Dione CAS NO 1062-64-2 is a high-purity synthetic corticosteroid derivative, a key intermediate in advanced pharmaceutical synthesis. This compound matters for its critical role in the development and production of potent anti-inflammatory and immunosuppressive medications. Pharmaceutical R&D laboratories and active pharmaceutical ingredient (API) manufacturers need this precise chemical building block to ensure the efficacy and consistency of final drug products.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of advanced corticosteroid APIs.
• Anti-inflammatory Drug Research: Used in the development of new therapeutic agents for treating conditions like arthritis, asthma, and dermatological disorders.
• Immunosuppressant Synthesis: Serves as a building block for compounds that modulate the immune system.
• Steroid Chemistry R&D: A valuable reference standard and starting material in academic and industrial steroid research programs.
• Process Development: Employed in scaling up and optimizing manufacturing routes for complex steroid molecules.
• Analytical Standard: Used as a high-purity standard for quality control and method validation in analytical laboratories.

Basic Information

Item	Details
Product Name	(11Beta,16Alpha)-9-Fluoro-11-Hydroxy-17,21-[(1-Methoxypentylidene)Bis(Oxy)]-16-Methylpregna-1,4-Diene-3,20-Dione
CAS No.	1062-64-2
Molecular Formula	C₂₈H₃₉FO₆
Molecular Weight	490.61 g/mol
Synonyms	9-Fluoro-11β,16α,17,21-tetrahydroxypregna-1,4-diene-3,20-dione cyclic 16,17-acetal with 1-methoxypentanal; Fluprednisolone 16,17-Acetonide (related analog); 16α-Methyl-9α-fluoro-1,4-pregnadiene-11β,17α,21-triol-3,20-dione cyclic 16,17-acetal with 1-methoxypentanal; Contact for additional synonyms.
EINECS	Contact for details

Quality Control

Our (11Beta,16Alpha)-9-Fluoro-11-Hydroxy-17,21-[(1-Methoxypentylidene)Bis(Oxy)]-16-Methylpregna-1,4-Diene-3,20-Dione is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific customer or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive (store away from light) and easily oxidized (store under inert atmosphere); it is recommended to store under an inert gas such as nitrogen or argon for long-term stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.