Description

Hydrocortamate Hydrochloride is a synthetic corticosteroid derivative, specifically the hydrochloride salt of hydrocortamate. This compound is valued for its potent anti-inflammatory and immunosuppressive properties, making it a critical intermediate in advanced pharmaceutical synthesis. It is primarily utilized by research institutions and pharmaceutical manufacturers developing topical and injectable corticosteroid formulations for treating dermatological and inflammatory conditions.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potent topical corticosteroid medications.
• Anti-inflammatory Agent Research: Used in preclinical and clinical research to study mechanisms of inflammation and immune response modulation.
• Dermatological Formulations: Incorporated into creams, ointments, and lotions for treating eczema, psoriasis, and contact dermatitis.
• Veterinary Medicine: Employed in the development of anti-inflammatory treatments for animals.
• Reference Standard: Serves as a high-purity analytical standard for quality control and regulatory testing in pharmaceutical labs.
• Biochemical Research: Used to investigate glucocorticoid receptor interactions and downstream signaling pathways.

Basic Information

Product Name	Hydrocortamate Hydrochloride
CAS No.	125-03-1
Molecular Formula	C23H32ClNO5
Molecular Weight	438.0 g/mol
Synonyms	Hydrocortisone 21-Diethylaminoacetate Hydrochloride; 11β,17α,21-Trihydroxypregn-4-ene-3,20-dione 21-(2-(Diethylamino)acetate) Hydrochloride; Hydrocortisone Diethylaminoacetate Hydrochloride; NSC-527579; Hydrocortamate HCl; WIN 24540; Hydrocortisone 21-N,N-Diethylglycinate Hydrochloride
EINECS	204-727-8

Quality Control

Our Hydrocortamate Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identification by IR and NMR spectroscopy, and tests for residual solvents and related substances, ensuring it meets stringent standards for pharmaceutical intermediates. Certificates of Analysis (COA) with full traceability are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry conditions to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.