Description

Fluocortolone Acetate is a synthetic corticosteroid ester with potent anti-inflammatory and immunosuppressive properties. This high-purity active pharmaceutical ingredient (API) is critical for the development and manufacturing of advanced topical and systemic corticosteroid formulations. It is primarily required by pharmaceutical manufacturers and research institutions engaged in dermatology, immunology, and inflammatory disease therapeutics.

Application

• Pharmaceutical API: Core active ingredient in prescription-strength topical creams, ointments, and lotions for treating severe eczema, psoriasis, and dermatitis.
• Dermatological Preparations: Used in compounded medications for targeted anti-inflammatory and anti-pruritic (anti-itch) therapy.
• Veterinary Medicine: Formulated into treatments for inflammatory skin conditions in animals.
• Clinical Research: Serves as a reference standard and key intermediate in pharmacological studies and new drug development.
• Systemic Corticosteroid Synthesis: Acts as a crucial precursor or intermediate in the synthesis of other fluorinated corticosteroid molecules.

Basic Information

Product Name	Fluocortolone Acetate
CAS No.	1176-82-5
Molecular Formula	C₂₄H₃₁FO₆
Molecular Weight	434.50 g/mol
Synonyms	6α-Fluoro-11β,21-dihydroxy-16α-methylpregna-1,4-diene-3,20-dione 21-acetate; 6α-Fluorocortisol 21-acetate; Fluocortolone 21-acetate; SH 968; Ultralan; Ultralanum; Flucort
EINECS	214-615-5

Quality Control

Our Fluocortolone Acetate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with ICH guidelines. A Certificate of Analysis (COA) detailing results for assay, related substances, residual solvents, and microbiological limits is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.