Description

Poly(Dc,Dg,M(6)Dg) is a specialized synthetic oligonucleotide derivative. This compound is a critical building block in advanced molecular biology and pharmaceutical research, offering precise control over genetic and biochemical interactions. It is essential for researchers and manufacturers in the biotechnology, diagnostic, and therapeutic development sectors who require high-purity, sequence-specific nucleic acid analogs.

Application

• Oligonucleotide Synthesis: Serves as a key phosphoramidite monomer for the solid-phase synthesis of modified DNA/RNA strands.
• Antisense & siRNA Therapeutics: Used in the development of gene-silencing drugs that target specific mRNA sequences.
• Molecular Diagnostics: Incorporated into probes and primers for PCR, sequencing, and microarray applications to enhance specificity and stability.
• Structural Biology Studies: Employed to investigate nucleic acid structure, function, and protein-nucleic acid interactions.
• Aptamer Development: A component in creating synthetic nucleic acid ligands (aptamers) for therapeutic and diagnostic use.
• Bioconjugation & Labeling: Acts as a substrate for attaching reporter molecules (e.g., fluorophores, biotin) to oligonucleotides.

Basic Information

Product Name	Poly(Dc,Dg,M(6)Dg)
CAS No.	76417-82-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	5'-O-Dimethoxytrityl-N2-isobutyryl-2'-deoxyguanosine,3'-[(2-cyanoethyl)-(N,N-diisopropyl)]-phosphoramidite; dG-Ibu Phosphoramidite; 2'-Deoxy-N2-isobutyrylguanosine 3'-(2-cyanoethyl N,N-diisopropylphosphoramidite); Guanosine, 2'-deoxy-N2-(2-methyl-1-oxopropyl)-, 3'-(2-cyanoethyl) N,N-diisopropylphosphoramidite, 5'-(bis(4-methoxyphenyl)phenylmethyl) ether; dG(ib) Phosphoramidite; N-Isobutyryl-2'-deoxyguanosine phosphoramidite
EINECS	Contact for details

Quality Control

Our Poly(Dc,Dg,M(6)Dg) is manufactured under strict quality systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity verification, to ensure it meets the high standards required for sensitive research and GMP-grade applications. A comprehensive Certificate of Analysis (COA) detailing purity, moisture content, and performance data is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (argon or nitrogen) in a dry, freezer. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to prevent condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Solubility	Soluble in anhydrous acetonitrile

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.