Description

2-Aminopurine Dihydrochloride is a high-purity biochemical building block and research compound, essential for advanced scientific and pharmaceutical development. Its primary value lies in its role as a fluorescent adenine analog, enabling critical studies in nucleic acid structure, dynamics, and enzyme interactions. This compound is particularly vital for researchers and manufacturers in pharmaceutical R&D, molecular biology, and diagnostic reagent production, where precise molecular tools are required.

Application

• Fluorescent Probe in Nucleic Acid Research: Used to study DNA and RNA structure, dynamics, and protein-nucleic acid interactions due to its base-pairing properties and intrinsic fluorescence.
• Enzyme Mechanism Studies: Serves as a substrate or inhibitor for enzymes like adenosine deaminase and various kinases, helping elucidate catalytic pathways.
• Antiviral and Anticancer Drug Discovery: Acts as a key intermediate or active scaffold in the synthesis and screening of novel therapeutic agents targeting purine metabolism.
• Diagnostic Assay Development: Incorporated into probes and assays for detecting specific genetic sequences or enzymatic activities in clinical and research settings.
• Biophysical Studies: Employed in fluorescence spectroscopy, FRET (Förster Resonance Energy Transfer), and other techniques to monitor real-time biomolecular processes.
• Academic and Industrial R&D: A fundamental reagent for chemical biology and medicinal chemistry programs in universities, biotech, and pharmaceutical companies.

Basic Information

Product Name	2-Aminopurine Dihydrochloride
CAS No.	76124-64-6
Molecular Formula	C5H7Cl2N5
Molecular Weight	208.05 g/mol
Synonyms	2-AP dihydrochloride; 2-Aminopurine hydrochloride; 2-Aminopurine HCl; 2-Aminohypoxanthine dihydrochloride; 2-Amino-1H-purine dihydrochloride; 2-Amino-9H-purine dihydrochloride; 2-Aminopurinium dichloride; Purin-2-amine dihydrochloride
EINECS	Contact for details

Quality Control

Our 2-Aminopurine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment to ensure traceability and compliance with your research or production standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept in a desiccated environment to prevent moisture absorption. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥98.0%
Water Content (KF)	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.