Description

Tetrocarcin A is a complex, biologically active natural product belonging to the family of tetrocarcin antibiotics, isolated from *Micromonospora* species. This compound is valued for its potent and specific inhibitory activity against the anti-apoptotic protein Bcl-2, making it a critical research tool in oncology and cell biology studies. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and biotechnology companies focused on cancer therapeutics and apoptosis signaling pathways.

Application

• Biomedical Research: Used as a selective inhibitor of Bcl-2 protein function in apoptosis (programmed cell death) studies.
• Oncology Drug Discovery: Serves as a lead compound and pharmacological probe for developing novel anti-cancer therapeutics targeting Bcl-2 family proteins.
• Mechanistic Studies: Employed in biochemical and cellular assays to investigate the role of mitochondrial pathways in cell survival and death.
• Academic Research: A key reagent for universities and research institutes studying cancer biology, protein-protein interactions, and small molecule inhibitors.
• High-Throughput Screening (HTS): Can be used as a reference standard in screening campaigns to identify new apoptosis modulators.

Basic Information

Product Name	Tetrocarcin A
CAS No.	73666-84-9
Molecular Formula	C₄₇H₆₀N₂O₁₈
Molecular Weight	953.0 g/mol
Synonyms	Tetrocarcin A1; Antibiotic Tetrocarcin A; NSC 339586; U-59501; Tetrocarcin A (Antibiotic from *Micromonospora*); Tetrocarcin
EINECS	Contact for details

Quality Control

Our Tetrocarcin A is produced and handled under strict quality management protocols to ensure batch-to-batch consistency and reliability for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and potency. We adhere to relevant industry standards for research-grade biochemicals, ensuring the material's integrity for sensitive biological assays.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This product is hygroscopic (moisture-sensitive) and easily oxidized; prolonged exposure to air, moisture, or light should be avoided to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 2.0%
Potency (Biological Assay)	Reported per COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.