Description

Trna, Leucine- CAS NO 73562-14-8 is a specialized biochemical compound, specifically a transfer RNA molecule charged with the amino acid leucine. This product is essential for research and development in molecular biology and biochemistry, where it serves as a critical tool for studying protein synthesis, tRNA function, and aminoacylation mechanisms. It is primarily needed by academic research institutions, biotechnology companies, and pharmaceutical developers focused on genetic translation, synthetic biology, and therapeutic target discovery.

Application

• Biochemical Research: Used as a substrate in studies of tRNA aminoacylation kinetics and enzyme specificity.
• Protein Synthesis Studies: Essential for in vitro translation systems to investigate the mechanisms of ribosome function and peptide bond formation.
• Diagnostic Development: Serves as a key component in the development of assays for aminoacyl-tRNA synthetase activity, relevant for certain genetic disorders.
• Enzymology: Employed to study the catalytic properties and inhibition of leucine-tRNA synthetase, a target for antimicrobial agents.
• Synthetic Biology: Used in engineered systems for incorporating non-canonical amino acids into proteins.
• Pharmaceutical R&D: Applied in high-throughput screening platforms to identify novel inhibitors of translation for therapeutic purposes.

Basic Information

Product Name	Trna, Leucine- CAS NO 73562-14-8
CAS No.	73562-14-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Leucyl-tRNA; L-Leucine-specific tRNA; tRNALeu; Leucine Transfer Ribonucleic Acid; Aminoacyl-tRNA(Leu); Leucine-charged tRNA; tRNA charged with L-leucine
EINECS	Contact for details

Quality Control

Our Trna, Leucine- is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and biological activity. Each lot is subjected to rigorous analytical testing, including assessment of aminoacylation efficiency and purity. Certificates of Analysis (COA) detailing specific purity, concentration, and functional activity are available upon request to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. For long-term stability, store at -20°C or below. Avoid repeated freeze-thaw cycles. Handle under appropriate laboratory conditions to maintain integrity.

Specification

Item	Specification
Appearance	White to off-white lyophilized powder
Identification (HPLC/LC-MS)	Conforms
Assay (Aminoacylation)	≥ 85% charged
Purity (HPLC)	≥ 90%
Biological Activity	Functional in in vitro translation
Endotoxin	< 1.0 EU/mg

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.