Description

Chloro(2,5-Dimethylphenyl)Magnesium is a highly reactive organomagnesium compound, specifically a Grignard reagent, widely used as a versatile building block in organic synthesis. Its core value proposition lies in its ability to act as a powerful nucleophile for the formation of carbon-carbon bonds, enabling the synthesis of complex molecules with high precision. This reagent is essential for researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries who require reliable, high-purity intermediates for developing active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate Synthesis: Key reagent for constructing complex molecular scaffolds in active pharmaceutical ingredient (API) development.
• Agrochemical Manufacturing: Used in the synthesis of herbicides, fungicides, and insecticides that require specific aryl group incorporation.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in homogeneous catalysis.
• Fine Chemical Production: Employed in the manufacture of dyes, pigments, and other performance chemicals where the 2,5-dimethylphenyl moiety is desired.
• Polymer and Material Science: Utilized to introduce functional aryl groups into polymer backbones or surface modifiers.
• Academic and R&D Laboratories: Fundamental tool for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	Chloro(2,5-Dimethylphenyl)Magnesium
CAS No.	71888-64-7
Molecular Formula	C8H9ClMg
Molecular Weight	164.91 g/mol
Synonyms	(2,5-Dimethylphenyl)magnesium chloride; Magnesium, chloro(2,5-dimethylphenyl)-; 2,5-Dimethylphenylmagnesium chloride; 1-Methyl-4-(chloromagnesio)-2-methylbenzene; p-Xylylmagnesium chloride (common name); Grignard reagent from 2,5-dimethylchlorobenzene
EINECS	Contact for details

Quality Control

Our Chloro(2,5-Dimethylphenyl)Magnesium is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, concentration (typically supplied as a solution in THF or diethyl ether), and the absence of protic impurities that can deactivate the reagent. Certificates of Analysis (COA) detailing titration results and other critical parameters are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This product is highly volatile and reacts violently with water and protic solvents. It must be stored under a dry, inert atmosphere (argon or nitrogen) at recommended temperatures between 2°C and 8°C to maintain stability and potency. Keep away from heat, sparks, open flames, and any source of moisture or oxygen.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Concentration (in THF)	0.5 M - 2.0 M (custom concentrations available)
Assay (by Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure
Water Content (Karl Fischer)	≤ 50 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.