Description

7-Deoxynogarol is a specialized anthracycline derivative and a key intermediate in the synthesis of complex bioactive molecules. This compound matters for its role in pharmaceutical research and development, particularly in the study of novel anticancer agents and topoisomerase inhibitors. It is primarily needed by research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers focused on oncology drug discovery and advanced synthetic chemistry.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel anthracycline-based chemotherapeutic agents.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action against cancer cell lines.
• Topoisomerase Inhibition Studies: Serves as a reference compound or precursor in research targeting DNA topoisomerase enzymes.
• Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies to develop analogs with improved efficacy and reduced toxicity.
• Academic Research: Utilized in university and institutional labs for chemical biology and anticancer drug discovery projects.
• Fine Chemical Synthesis: A high-value intermediate for contract research organizations (CROs) and CDMOs specializing in complex molecule manufacturing.

Basic Information

Product Name	7-Deoxynogarol
CAS No.	71582-53-1
Molecular Formula	C26H29NO9
Molecular Weight	499.51 g/mol
Synonyms	7-Deoxynogalarol; Nogalarol, 7-deoxy-; (7S,9S)-9-Acetyl-7-[(2S,4S,5S,6S)-4-(dimethylamino)-5-hydroxy-6-methyloxan-2-yl]oxy-6,9,11-trihydroxy-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione; 4-Demethoxy-7-deoxydaunorubicin; 7-Deoxy-4-demethoxydaunorubicin; Anthracycline intermediate; 7-DNOL
EINECS	Contact for details

Quality Control

Our 7-Deoxynogarol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to orange-red powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 5.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.