Description

Bromomagnesium[1-(Dimethylamino)-1-Propanolate] is a highly reactive organomagnesium reagent, specifically a magnesium alkoxide complex. This compound is valued for its dual functionality as a strong base and a nucleophile, enabling precise and efficient transformations in advanced synthetic chemistry. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and fine chemical industries for the synthesis of complex molecules, including active pharmaceutical ingredients (APIs) and specialty intermediates.

Application

• Pharmaceutical Synthesis: A key reagent for the formation of carbon-carbon and carbon-heteroatom bonds in the multi-step synthesis of novel drug candidates and APIs.
• Fine Chemical Manufacturing: Employed in the production of high-value specialty chemicals, agrochemical intermediates, and advanced materials requiring controlled metallation reactions.
• Academic & Industrial R&D: Used in method development and exploratory chemistry for creating new molecular libraries and investigating reaction mechanisms.
• Catalyst and Ligand Preparation: Serves as a precursor or reactant in the synthesis of tailored catalysts and complex ligands for asymmetric synthesis and polymerization processes.
• Dehydrohalogenation and Deprotonation Reactions: Effective for regioselective deprotonation of sensitive substrates where milder bases are insufficient.

Basic Information

Product Name	Bromomagnesium[1-(Dimethylamino)-1-Propanolate]
CAS No.	71077-40-2
Molecular Formula	C5H12BrMgNO
Molecular Weight	182.36 g/mol
Synonyms	Magnesium, bromo[1-(dimethylamino)-1-propanolato]-; Bromo[1-(dimethylamino)-1-propanolato]magnesium; 1-Propanol, 1-(dimethylamino)-, magnesium complex; (1-(Dimethylamino)-1-propanolato)bromomagnesium; Grignard Reagent Derivative; Magnesium alkoxide complex; Bromomagnesium dimethylaminopropoxide
EINECS	Contact for details

Quality Control

Every batch of Bromomagnesium[1-(Dimethylamino)-1-Propanolate] is manufactured and tested under strict quality management protocols. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, assay, and solvent content are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This material is easily oxidized (store under inert atmosphere) and reacts as a strong base/organic solvent. For long-term stability, store under a dry, inert atmosphere (argon or nitrogen) at a controlled room temperature (15-25°C). Keep away from moisture, heat, and incompatible materials such as acids and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 0.5 M in specified solvent (e.g., THF)
Purity (NMR/HPLC)	Contact for details
Solvent	Specified (e.g., Tetrahydrofuran)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.