Description

n-Ethyl-13-Dihydrorubomycin is a semi-synthetic anthracycline derivative, a class of compounds renowned for their potent biological activity. This chemical is of significant interest in pharmaceutical research and development, particularly for its potential as a key intermediate or active pharmaceutical ingredient (API) in oncology. It is primarily needed by research institutions, pharmaceutical manufacturers, and fine chemical suppliers engaged in the development of novel chemotherapeutic agents and advanced drug delivery systems.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel anthracycline-based anticancer drugs.
• Oncology Research: Used in biochemical and pharmacological studies to investigate mechanisms of action, structure-activity relationships (SAR), and cytotoxicity profiles.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• API Synthesis: Acts as a precursor in the multi-step synthesis of complex therapeutic agents targeting DNA intercalation and topoisomerase II inhibition.
• Bioconjugation Studies: Utilized in research exploring antibody-drug conjugates (ADCs) or other targeted delivery systems for improved cancer therapy.

Basic Information

Product Name	n-Ethyl-13-Dihydrorubomycin
CAS No.	70844-03-0
Molecular Formula	C29H33NO11
Molecular Weight	571.57 g/mol
Synonyms	13-Ethyl-13-dihydrodaunorubicin; 4-Demethoxydaunorubicin derivative; 13-Ethyl-13-dihydrodaunomycin; IDA-13-ethyl derivative; Rubidazone analog; 13-Ethyl-13-dihydro-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[(2,3,6-trideoxy-3-amino-α-L-lyxo-hexopyranosyl)oxy]-5,12-naphthacenedione; 13-Ethyl-13-dihydro-7,8,9,10-tetrahydro-6,8,11-trihydroxy-8-(hydroxyacetyl)-1-methoxy-10-[(2,3,6-trideoxy-3-amino-α-L-lyxo-hexopyranosyl)oxy]-5,12-naphthacenedione
EINECS	Contact for details

Quality Control

Our n-Ethyl-13-Dihydrorubomycin is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) detailing all specifications and test results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. The container should be kept in a cool, dry, and well-ventilated area.

Specification

Item	Specification
Appearance	Orange to red powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.