Description

Methylmagnesium Bromide CAS NO 75-16-1 is a fundamental organometallic reagent, specifically a Grignard reagent, widely used for nucleophilic addition and carbon-carbon bond formation. Its primary commercial value lies in its ability to efficiently introduce methyl groups into a wide range of organic substrates, serving as a critical building block in complex synthesis. This compound is essential for R&D chemists and production facilities in the pharmaceutical, agrochemical, and fine chemical industries where precise methylations are required.

Application

• Pharmaceutical Intermediates: Key reagent in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing methyl groups into complex molecular frameworks.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and pesticides where specific methylation steps are crucial for bioactivity.
• Fine Chemical Manufacturing: Employed in the synthesis of specialty chemicals, flavors, fragrances, and advanced materials.
• Polymer Chemistry: Acts as an initiator or catalyst in certain polymerization reactions and in the modification of polymer chains.
• Academic & Industrial R&D: A staple reagent in research laboratories for methodological development and exploratory synthesis of novel organic compounds.
• Electrolyte Additives: Investigated for use in the formulation of advanced battery electrolytes.

Basic Information

Product Name	Methylmagnesium Bromide
CAS No.	75-16-1
Molecular Formula	CH3MgBr
Molecular Weight	119.24 g/mol
Synonyms	Methylmagnesium Bromide Solution; Bromo(methyl)magnesium; Methyl Grignard Reagent; Magnesium, bromomethyl-; Methylmagnesium bromide (1M in THF); Methylmagnesium bromide (3M in diethyl ether); Methyl magnesium bromide; Grignard reagent, CH3MgBr
EINECS	200-843-6

Quality Control

Our Methylmagnesium Bromide is produced under stringent quality management systems. Each batch undergoes rigorous analytical testing, including titration for assay determination and impurity profiling, to ensure high consistency and reliability for your synthetic processes. Certificates of Analysis (COA) detailing concentration, solvent content, and impurity levels are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) in a cool, dry, well-ventilated area. Due to its highly volatile and moisture-sensitive nature, it must be handled and stored away from heat, sparks, and open flame. Typical storage temperature is 2-8°C for extended stability, although specific recommendations depend on the solvent system (e.g., THF or diethyl ether solution).

Specification

Item	Specification
Appearance	Clear, colorless to slightly yellow solution
Concentration (Typical)	1.0 M in THF or 3.0 M in Diethyl Ether
Assay (Titration)	≥ 95.0%
Identification (IR)	Conforms
Water Content (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.