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3-Methyl-2-Pyridylmagnesium Bromide CAS NO 661458-30-6


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CAS No.:661458-30-6

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

3-Methyl-2-Pyridylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, widely used in synthetic organic chemistry for the formation of carbon-carbon bonds. Its primary value lies in its ability to act as a nucleophile, introducing the 3-methyl-2-pyridyl moiety into target molecules with high efficiency. This compound is particularly essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it serves as a key building block in the synthesis of complex heterocyclic compounds, active pharmaceutical ingredients (APIs), and advanced materials.

Application

  • Pharmaceutical Intermediates: A critical building block for synthesizing novel drug candidates, especially those containing pyridine-based heterocycles.
  • Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides that require specific pyridyl functional groups.
  • Material Science Research: Employed in the development of organic ligands for catalysts, metal-organic frameworks (MOFs), and functional polymers.
  • Fine Chemical Production: Facilitates the synthesis of specialty chemicals, flavors, and fragrances through precise carbon-carbon bond formation.
  • Academic & R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name 3-Methyl-2-Pyridylmagnesium Bromide
CAS No. 661458-30-6
Molecular Formula C6H6BrMgN
Molecular Weight 196.32 g/mol
Synonyms 2-(3-Methylpyridyl)magnesium bromide; (3-Methyl-2-pyridinyl)magnesium bromide; 3-Methylpyrid-2-ylmagnesium bromide; Magnesium, bromo(3-methyl-2-pyridinyl)-; 3-Methyl-2-pyridyl Grignard reagent; 3-Methyl-2-pyridinemagnesium bromide
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Quality Control

Our 3-Methyl-2-Pyridylmagnesium Bromide is manufactured under stringent quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot undergoes rigorous analytical testing, including titration for assay determination and impurity profiling. Certificates of Analysis (COA) detailing purity, concentration, and solvent are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. This material is moisture-sensitive (hygroscopic) and should be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. For extended stability, storage at 2-8°C is recommended. Always handle and store away from moisture and incompatible materials.

Specification

Item Specification
Appearance Solution (typically in THF or Diethyl Ether)
Identification (IR) Conforms
Assay (Titration) 0.5 M in THF (or as specified)
Purity (HPLC) ≥ 95% (Area %)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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