Description

5-Methyl-2-Pyridylmagnesium Bromide is a versatile organometallic reagent, specifically a Grignard reagent, essential for forming carbon-carbon bonds in complex organic syntheses. Its primary value lies in its ability to act as a nucleophile, introducing the 5-methyl-2-pyridyl moiety into target molecules with high efficiency and selectivity. This compound is critically needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing active pharmaceutical ingredients (APIs), novel crop protection agents, and functional ligands.

Application

• Pharmaceutical Intermediate Synthesis: Key building block for the preparation of drug candidates, particularly those containing pyridine-based heterocycles.
• Agrochemical Development: Used in the synthesis of novel herbicides, fungicides, and insecticides that require the 5-methyl-2-pyridyl functional group.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as charge-transport layers or light-emitting compounds.
• Fine Chemical Production: Facilitates the scalable manufacture of complex, high-value specialty chemicals for various industrial applications.
• Academic and R&D Laboratories: A fundamental reagent for methodological development and exploratory synthesis in organic chemistry.

Basic Information

Product Name	5-Methyl-2-Pyridylmagnesium Bromide
CAS No.	661458-29-3
Molecular Formula	C6H6BrMgN
Molecular Weight	196.32 g/mol
Synonyms	2-(5-Methylpyridyl)magnesium bromide; (5-Methylpyridin-2-yl)magnesium bromide; 5-Methyl-2-pyridinylmagnesium bromide; 5-Methyl-2-pyridyl Grignard reagent; Magnesium, bromo(5-methyl-2-pyridinyl)-; 2-Pyridylmagnesium bromide, 5-methyl-; 5-Methyl-2-bromomagnesio-pyridine
EINECS	Contact for details

Quality Control

Our 5-Methyl-2-Pyridylmagnesium Bromide is produced and handled under stringent quality protocols to ensure batch-to-batch consistency and reliability for your critical syntheses. Quality is assured through comprehensive analytical testing, including titration for Grignard concentration and GC/HPLC analysis for purity and solvent content. A Certificate of Analysis (COA) detailing all relevant specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. This compound is easily oxidized (store under inert atmosphere) and highly volatile. It must be stored under an inert gas atmosphere (argon or nitrogen) in a cool, dry, and well-ventilated area, away from heat and moisture sources. For optimal stability, storage at 2-8°C is recommended. Keep away from incompatible materials such as strong acids, water, and oxidizing agents.

Specification

Item	Specification
Appearance	Clear to slightly colored solution
Concentration (in THF or Ether)	0.5 M - 2.0 M (Custom concentrations available)
Assay (by Titration)	≥ 95%
Purity (GC/HPLC)	Contact for details
Solvent	Specified (Tetrahydrofuran, Diethyl ether, or other)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.