Description

6-Methyl-2-Pyridylmagnesium Bromide is a highly reactive organometallic reagent, specifically a Grignard reagent, essential for forming new carbon-carbon bonds in complex organic synthesis. Its primary value lies in its ability to act as a nucleophile, introducing the 6-methyl-2-pyridyl moiety into target molecules with high precision. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries for constructing heterocyclic scaffolds and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate Synthesis: Key building block for the preparation of novel drug candidates, particularly those containing pyridine-based heterocycles.
• Agrochemical Development: Used in the synthesis of advanced pesticides, herbicides, and fungicides that require specific pyridyl functional groups.
• Ligand and Catalyst Preparation: Serves as a precursor for synthesizing specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the creation of organic electronic materials, such as those used in OLEDs and conductive polymers.
• Custom Chemical Synthesis: A versatile reagent for contract research organizations (CROs) and fine chemical manufacturers performing bespoke synthesis for clients.
• Academic Research: Fundamental tool in university and institutional labs for methodological development and exploring new reaction pathways.

Basic Information

Product Name	6-Methyl-2-Pyridylmagnesium Bromide
CAS No.	621685-64-1
Molecular Formula	C6H6BrMgN
Molecular Weight	196.32 g/mol
Synonyms	2-(6-Methylpyridyl)magnesium bromide; 6-Methyl-2-pyridylmagnesium bromide solution; (6-Methylpyridin-2-yl)magnesium bromide; Magnesium, bromo(6-methyl-2-pyridinyl)-; 2-Pyridylmagnesium bromide, 6-methyl-; Grignard reagent 6-methyl-2-pyridyl; 6-Methyl-2-pyridyl Grignard reagent
EINECS	Contact for details

Quality Control

Every batch of 6-Methyl-2-Pyridylmagnesium Bromide is manufactured and handled under strict inert atmosphere conditions to ensure reactivity and purity. Our products undergo rigorous quality testing, including titration for assay and GC analysis for solvent consistency, to ensure compliance with exacting R&D and process chemistry standards. Certificates of Analysis (COA) detailing concentration, solvent, and quality parameters are provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (argon or nitrogen) at 2-8°C to maintain stability and prevent decomposition. Due to its highly volatile and pyrophoric nature in certain concentrations, keep away from heat, sparks, and open flames. Handle only in a certified fume hood using appropriate techniques for air-sensitive reagents.

Specification

Item	Specification
Appearance	Clear, colorless to light brown solution
Concentration	Typically 0.5 M in THF or Diethyl Ether
Assay (by Titration)	≥ 95%
Identification (IR/NMR)	Conforms to structure

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.